SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Antiretroviral therapy and the risk of sexual transmission of HIV: A systematic review and meta-analysis

2020

OBJECTIVES: The aim of this study was to evaluate the effect of antiretroviral therapy (ART) with or without condom use on the risk of sexual transmission of HIV. METHODS: A...

Experiences and attitudes of people with HIV/AIDS: A systematic review of qualitative studies

2020

The aim of this article was to explore the experiences and attitudes of people with HIV/AIDS. A systematic review of qualitative studies was carried out. Twenty-seven articles were included, with...

Adolescent participation in HIV research: Consortium experience in low and middle-income countries and scoping review

2020

Adolescents in low and middle-income countries (LMICs) have a high prevalence of HIV, therefore, it is important that they are included in HIV research. However, ethical challenges regarding consent can...

HIV, vascular risk factors, and cognition in the combination antiretroviral therapy era: A systematic review and meta-analysis

2020

OBJECTIVES: Mounting evidence indicates that vascular risk factors (VRFs) are elevated in HIV and play a significant role in the development and persistence of HIV-associated neurocognitive disorder. Given the increased...

Are patient outcomes improved by models of professionally-led community HIV management which aim to be person-centred? A systematic review of the evidence

2020

UNAIDS advocates person-centred care (PCC) for people living with HIV/AIDS (PLWHA) to improve outcomes and wellbeing. We appraised the evidence of person-centred models of community HIV care delivered or led...

Global prevalence and burden of HIV-associated neurocognitive disorder: A meta-analysis

2020

OBJECTIVES: We aimed to characterise the prevalence and burden of HAND and assess associated factors in the global population with HIV. METHODS: We searched PubMed and Embase for cross-sectional or...

Kidney Transplantation in HIV Positive Patients: Current Practice and Management Strategies

2020

BACKGROUND: HIV positive patients had been successfully transplanted for the last 15 years and the donor pool had successfully been expanded to also include HIV positive donors. METHODS: We aimed...

Immune checkpoint inhibitor therapy for cancer patients infected with HIV: A systematic review

2020

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy represents a breakthrough in cancer treatment. However, clinical trials of ICI have usually excluded people living with HIV (PLWH). The efficacy and safety data...

Effect of omega-3 polyunsaturated fatty acids treatment on lipid pattern of HIV patients: A meta-analysis of randomized clinical trials

2020

Even though omega-3 polyunsaturated fatty acids (PUFAs) seem to be effective in the treatment of human immunodeficiency virus (HIV)-associated dyslipidemia, their impact is still debated. For this reason, our aim...

Coronavirus disease 2019 (COVID-19) outcomes in HIV/AIDS patients: A systematic review

2020

OBJECTIVES: The aim of the study was to systematically review current studies reporting on clinical outcomes in people living with HIV (PLHIV) infected with severe acute respiratory syndrome coronavirus 2...

Mortality among people With opioid use disorder: A systematic review and meta-analysis

2020

BACKGROUND AND AIMS: Opioids are among the most commonly used class of illicit drugs. We aimed to produce pooled estimates of mortality risks among people with opioid use disorder (OUD),...

Mobile health promotion of human immunodeficiency virus self-testing in the United States

2020

Background: Human immunodeficiency virus (HIV) self-testing could overcome barriers associated with traditional HIV testing and increase people’s awareness of their serostatus. Mobile health, which utilizes mobile wireless technology, could alleviate...

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