SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Barriers and facilitators for the sexual and reproductive health and rights of young people in refugee contexts globally: A scoping review

2020

BACKGROUND: The need to address sexual and reproductive health and rights (SRHR) in humanitarian settings is more urgent than ever, especially among young refugees. We conducted a scoping review to...

Systematic review of interventions to reduce HIV risk among men who purchase sex in low- and middle-income countries: Outcomes, lessons learned, and opportunities for future interventions

2020

Along with other partners of key population groups, men who purchase sex (MWPS) contributed to around 18% of new reported HIV cases in 2018 among people aged 15-49 years worldwide....

The pharmacogenetics of efavirenz metabolism in children: The potential genetic and medical contributions to child development in the context of long-term ARV treatment

2020

Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between...

Difference in toxicity between HIV-positive and HIV-negative patients with squamous-cell cancer of the anal canal treated with concomitant radio-chemotherapy

2020

Background: The incidence of squamous cell carcinoma of the anal canal has been increasing over the last 30 years. HIV has been found to be a risk factor for the...

Determinants of preterm birth among mothers who gave birth in East Africa: Systematic review and meta-analysis

2020

BACKGROUND: Preterm birth (PTB) can be caused by different factors. The factors can be classified into different categories: socio demographic, obstetric, reproductive health, medical, behavioral and nutritional related. The objective...

The magnitude of adherence to option B plus program and associated factors among women in eastern African countries: A systematic review and meta-analysis

2020

Background: Despite coverage and benefits associated with the prevention of mothers to child transmission (PMTCT) services, mothers’ adherence to option B plus is still a challenge. Though few primary studies...

Social and demographical determinants of quality of life in people who live with HIV/AIDS infection: Evidence from a meta-analysis

2020

The aim of this meta-analysis is to summarize the available evidence on the social and demographic determinants of health-related quality of life (QoL) for HIV-infected populations in order to provide...

Sexually transmitted infections in pregnancy: A narrative review of the global research gaps, challenges, and opportunities

2020

BACKGROUND: Sexually transmitted infections (STI), such as chlamydial, gonorrheal, and trichomonal infection, are prevalent in pregnant women in many countries and are widely reported to be associated with increased risk...

Cancer in youth living with HIV (YLWHIV): A narrative review of the access to oncological services among YLWHIV and the role of economic strengthening in child health

2020

Youth Living with HIV/AIDS (YLWHIV) have a higher risk of developing immunodeficiency related illnesses including certain cancers than their general population counterparts of the same age. This narrative review of...

Quality of life of people with HIV/AIDS in Iran: A systematic review and meta-analysis

2020

BACKGROUND: Assessing the quality of life in HIV/AIDS patients is of great importance not only for evaluating the effect of the disease, but also to measure the impact of the...

A comparative analysis of blood pressure in HIV-infected patients versus uninfected controls residing in Sub-Saharan Africa: A narrative review

2020

Elevated blood pressure (BP) is an important risk factor for cardiovascular disease and mortality in Sub-Saharan Africa (SSA). We reviewed the literature comparing BP in treated HIV-infected populations against untreated...

Barriers to older adults seeking sexual health advice and treatment: A scoping review

2020

BACKGROUND: Sexual health is an integral part of overall health in older age. Research consistently reports that heterosexual and queer older people tend not to disclose sexual concerns and difficulties...

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