SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A review of potential microbiome-gut-brain axis mediated neurocognitive conditions in persons living with HIV

2020

The microbiome-gut-brain axis, or the various interactions between the gut microbiome and the brain, has been of recent interest in the context of precision medicine research for a variety of...

Are sexually transmitted infection/HIV behavioral interventions for women of color culturally grounded? A review of the literature

2020

Although behavioral interventions for women of color have been shown to be effective in reducing sexually transmitted infections (STIs), STI/HIV rates continue to increase. To alleviate sexual health disparities, it...

Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living with HIV: Systematic review and meta-analysis of diagnostic test accuracy studies

2020

Cryptococcal antigen (CrAg) detection could direct timely initiation of antifungal therapy. We searched MEDLINE and EMBASE for studies where CrAg detection in serum/cerebrospinal fluid (CSF) and CSF fungal culture were...

Effectiveness of financial incentives in achieving UNAID fast-track 90-90-90 and 95-95-95 target of HIV care continuum: A systematic review and meta-analysis of randomized controlled trials

2020

Financial incentives influence behavioural changes and the current review was done to assess the effectiveness of this intervention in improving HIV care continuum. We conducted systematic searches in MEDLINE, Cochrane...

Diagnostic accuracy of serum (1,3)-beta-D-glucan for Pneumocystis jirovecii pneumonia: A systematic review and meta-analysis

2020

Serum 1,3-β-d-glucan (BG) assay may be helpful as a marker for the diagnosis of Pneumocystis jiroveci pneumonia (PJP) and invasive fungal infection (IFI). We conducted a systematic review to assess the diagnostic...

Injecting risk behaviours amongst people who inject drugs: A global multi-stage systematic review and meta-analysis

2020

BACKGROUND: Injecting risk behaviour, such as receptive sharing of injecting equipment and/or re-using one’s equipment, is associated with bloodborne virus transmission and infections in people who inject drugs (PWID). We...

Attributes of HIV infection over decades (1982–2018): A systematic review and meta-analysis

2020

Understanding the risk factors for HIV infection is the foundation of successful preventive strategies, which must bundle sociocultural, behavioural and biomedical interventions to halt disease transmission. We aimed in this...

Prevalence estimates of human immunodeficiency virus (HIV) infection among visceral leishmaniasis infected people in Northwest Ethiopia: A systematic review and meta-analysis

2020

BACKGROUND: In Ethiopia, by the end of 2018, an estimated 690,000 people are infected with HIV and the annual cases of Visceral Leishmaniasis (VL) is estimated to be between 4000...

Nature and extent of hearing loss in HIV-infected children: A scoping review

2020

INTRODUCTION: Antiretroviral therapy (ART) has had a major impact on life expectancy from HIV as many people now live with it as a chronic disease. Chronic HIV has been associated...

The role of networks in racial disparities in HIV incidence among men who have sex with men in the United States

2020

Network factors have been proposed as potential drivers of racial disparities in HIV among Black and Latino men who have sex with men (MSM). This review aimed to synthesize the...

Immunogenicity of pneumococcal vaccination in HIV infected individuals: A systematic review and meta-analysis

2020

Background: The objective of this systematic review and meta-analysis was to summarise the literature regarding the immunogenicity of pneumococcal conjugate vaccines (PCV) and pneumococcal polysaccharide vaccines (PPSV) in adult people...

Clinical impact of pretreatment human immunodeficiency virus drug resistance in people initiating nonnucleoside reverse transcriptase inhibitor-containing antiretroviral therapy: A systematic review and meta-analysis

2020

BACKGROUND: Increased access to antiretroviral therapy (ART) has resulted in rising levels of pretreatment human immunodeficiency virus drug resistance (PDR). This is the first systematic review and meta-analysis to assess...

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