SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The safety and efficacy of marijuana in persons living with HIV

2019

The prevalence of the use of marijuana throughout the world is substantial. In light of ongoing increases in accessibility to marijuana, safety and efficacy must be established to guide recommendations...

HBV infection in HIV-driven immune suppression

2019

Worldwide, approximately 10% of all human immunodeficiency virus (HIV)-infected people are also chronically coinfected with hepatitis B virus (HBV). HBV infection has a poor prognosis in HIV-positive people and has...

Household-focused interventions to enhance the treatment and management of HIV in low- and middle-income countries: A scoping review

2019

BACKGROUND: HIV remains a major public health challenge in many low- and middle-income countries (LMICs). The initiation of a greater number of people living with HIV (PLHIV) onto antiretroviral therapy...

Unmet needs of Indigenous peoples living with HIV

2019

Key take-home messages In 2016, First Nations, Métis, and Inuit peoples accounted for 4.9% of the Canadian population but represented 11.3% of all new HIV infections. When considering Indigenous health,...

Prevention of mother-to-child transmission (PMTCT) of HIV: A review of the achievements and challenges in Burkina-Faso

2019

Background: Burkina-Faso’s HIV/AIDS program is one of the most successful in Africa, with a declining HIV prevalence and treatment outcomes that rival those of developed countries. Prevention of mother-to-child transmission...

Abnormal QTc syndrome in HIV-infected patients: A systematic review of prevalence and risk factors

2019

BACKGROUND: The purpose of this review is to critically analyze data regarding the prevalence and risk factors for developing a prolonged QTc interval and subsequent sudden cardiac death (SCD) in...

Recent interventions to improve retention in HIV care and adherence to antiretroviral treatment among adolescents and youth: A systematic review

2019

Adolescents represent a growing proportion of people living with HIV worldwide and the highest risk population group for treatment attrition and AIDS-related mortality. There is an urgent need to design,...

Second-line HIV treatment failure in sub-Saharan Africa: A systematic review and meta-analysis

2019

BACKGROUND: Increased second-line antiretroviral therapy (ART) failure rate narrows future options for HIV/AIDS treatment. It has critical implications in resource-limited settings; including sub-Saharan Africa (SSA) where the burden of HIV-infection...

Challenges and support for quality of life of youths living with HIV/AIDS in schools and larger community in East Africa: A systematic review

2019

BACKGROUND: Youths living with HIV/AIDS (YLWHA) experience innumerable challenges within schools and the larger community. Nonetheless, these environments are potential sources of support for such youths. This review provides a...

Accuracy of anal cytology for diagnostic of precursor lesions of anal cancer: Systematic review and meta-analysis

2019

BACKGROUND: Anal canal carcinoma is relevant because it commonly occurs in high-risk groups, and its incidence has been increasing. OBJECTIVE: This study evaluated the accuracy of anal cytology in the...

A scoping review on the role of masculine norms in men’s engagement in the HIV care continuum in sub-Saharan Africa

2019

Men living with HIV/AIDS in sub-Saharan Africa are less likely than women to be engaged at each stage of the HIV care continuum. We conducted a scoping review in May...

Acceptance of opt-out HIV screening in outpatient settings in the United States: A systematic review and meta-analysis

2019

OBJECTIVES: In the United States, about 15% of persons living with HIV infection do not know they are infected. Opt-out HIV screening aims to normalize HIV testing by performing an...

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