SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Virologically suppressed HIV-infected patients on TDF-containing regimens significantly benefit from switching to TAF-containing regimens: A meta-analysis of randomized controlled trials

2019

BACKGROUND: To investigate whether TDF-containing regimens significantly benefited efficacy, safety, and tolerability in TAF-containing regimens in virologically suppressed HIV-infected patients. METHODS: PubMed, Embase, Web of Science, and the Cochrane T

Is co-location of services with HIV care associated with improved HIV care outcomes? A systematic review

2019

This systematic review identifies models of service co-location, a structural intervention strategy to remove barriers to HIV care and services, and examines their associations with HIV care outcomes. A cumulative...

Retest and treat: A review of national HIV retesting guidelines to inform elimination of mother-to-child HIV transmission (EMTCT) efforts

2019

INTRODUCTION: High maternal HIV incidence contributes substantially to mother-to-child HIV transmission (MTCT) in some settings. Since 2006, HIV retesting during the third trimester and breastfeeding has been recommended by the...

Progressive disseminated histoplasmosis in Latin America and the Caribbean in people receiving highly active antiretroviral therapy for HIV infection: A systematic review

2019

Histoplasmosis is the most clinically significant mycosis in Latin America; still it has been neglected in people with human immunodeficiency virus (HIV). There is limited information about its contribution to...

ART adherence clubs in the Western Cape of South Africa: What does the sustainability framework tell us? A scoping literature review

2019

INTRODUCTION: In 2007, the antiretroviral therapy (ART) adherence club (AC) model was introduced to South Africa to combat some of the health system barriers to ART delivery, such as staff...

Crowdsourcing methods to enhance HIV and sexual health services: A scoping review and qualitative synthesis

2019

BACKGROUND: Crowdsourcing is increasingly used to improve community engagement in HIV and sexual health research. In this scoping review, we reviewed studies using crowdsourcing approaches in HIV and sexual health...

Sero-positive HIV result disclosure to sexual partner in Ethiopia: A systematic review and meta-analysis

2019

BACKGROUND: The infection of HIV continues to be an important public health problem in Ethiopia. Disclosing own HIV positive result is crucial, and considered as a good indicator of behavior...

Mind-body practices for people living with HIV: A systematic scoping review

2019

BACKGROUND: Mind-body practices are frequently used by people living with HIV to reduce symptoms and improve wellbeing. These include Tai Chi, Qigong, yoga, meditation, and all types of relaxation. Although...

Combined antiretroviral therapy for HIV and the risk of hypertensive disorders of pregnancy: A systematic review

2019

OBJECTIVE: To assess if there is a relationship between use of combined antiretroviral therapy among pregnant women living with HIV and hypertensive disorders of pregnancy (HDP). DESIGN: Due to the...

The association of memory disorders and chronic HIV disease in the antiretroviral therapy era: A systematic literature review

2019

OBJECTIVES: Despite recent pharmacological progress, memory impairment is still frequently reported in people living with HIV. We aimed to conduct a systematic literature review investigating the presence of impairment of...

Precancerous cervical lesion among HIV-positive women in sub-Saharan Africa: A systematic review and meta-analysis

2019

In sub-Saharan Africa, cervical cancer is an intersecting epidemic with HIV and it is the second most common cause of cancer-related deaths in women. Therefore, this study was aimed to...

Risk factors for indeterminate interferon-gamma release assay for the diagnosis of tuberculosis in children-A systematic review and meta-analysis

2019

Background: Interferon-gamma release assays (IGRA) are well-established immunodiagnostic tests for tuberculosis (TB) in adults. In children these tests are associated with higher rates of false-negative and indeterminate results. Age is...

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