SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV and other sexually transmitted infections among female sex workers in Iran: A systematic review and meta-analysis

2019

Given the high burden of HIV and other sexually transmitted infections (STIs) among female sex workers (FSW) and their potential role in bridging HIV/STIs into the general population, estimating the...

Burden of anemia and its association with HAART in HIV infected children in Ethiopia: A systematic review and meta-analysis

2019

BACKGROUND: Anemia is a common problem in HIV (human immunodeficiency virus) infected patients, and is associated with decreased functional capacity and quality of life. Ethiopia is one of the countries...

Epidemiology of Chlamydia trachomatis in the Middle East and North Africa: A systematic review, meta-analysis, and meta-regression

2019

BACKGROUND: The epidemiology of Chlamydia trachomatis in the Middle East and north Africa is poorly understood. We aimed to provide a comprehensive epidemiological assessment of C trachomatis infection in the...

Leveraging the lessons learned from financing HIV programs to advance the universal health coverage (UHC) agenda in the East African community

2019

Background: Although there is broad consensus around the need to accelerate progress towards universal health coverage (UHC) in Sub-Saharan Africa, the financing strategies for achieving it are still unclear. We...

Meta-analysis of the associations of CYP2B6-516G>T polymorphisms with efavirenz-induced central nervous system side effects and virological outcome in HIV-infected adults

2019

Clinical data on the relationships of cytochrome P450 (CYP2) B6 516G>T polymorphisms with efavirenz-induced central nervous system (CNS) side effects and virological response in HIV-infected adults are controversial. We sought...

Integration of HIV testing services into family planning services: A systematic review

2019

BACKGROUND: Despite significant interest in integrating sexual and reproductive health (SRH) services into HIV services, less attention has been paid to linkages in the other direction. Where women and girls...

The role of killer immunoglobulin-like receptor genes in susceptibility to HIV-1 infection and disease progression: A meta-analysis

2019

Genetic studies on the association of the killer immunoglobulin-like receptor (KIR) genes with HIV-1 infection and disease progression have been widely carried out with somewhat contradictory results. Therefore, we undertook...

Implementation science and stigma reduction interventions in low- and middle-income countries: A systematic review

2019

BACKGROUND: Interventions to alleviate stigma are demonstrating effectiveness across a range of conditions, though few move beyond the pilot phase, especially in low- and middle-income countries (LMICs). Implementation science offers...

Vaccination among HIV-infected, HIV-exposed uninfected and HIV-uninfected children: A systematic review and meta-analysis of evidence related to vaccine efficacy and effectiveness

2019

Evidence-based approaches were used in making recommendations for vaccination against vaccine-preventable diseases for HIV-infected and HIV-exposed individuals but with limited substantiation. We conducted a systematic review and meta-analysis with randomised-controlled...

The role of the clinical pharmacist in the management of people living with HIV in the modern antiretroviral era

2019

As the HIV epidemic has evolved, so too has the role of the clinical pharmacist (CP) in the management of people living with HIV (PLWH). The modern antiretroviral therapy (ART)...

MicroRNAs and exosomes: Key players in HIV pathogenesis

2019

OBJECTIVES: HIV infection is well known to cause impairment of the human immune system, and until recently was a leading cause of death. It has been shown that T lymphocytes...

Different transmission routes and the risk of advanced HIV disease: A systematic review and network meta-analysis of observational studies

2019

Background: A substantial proportion of people living with HIV (PLHIV) present for care with advanced HIV disease (AHD), which may result in difficulty reaching the “90-90-90” target to end AIDS...

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