SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Barriers and facilitators to engagement with the PrEP care continuum among sexual minority men in China: A systematic review

2025

Sexual minority men (SMM) in China are disproportionately affected by the HIV epidemic, yet utilization of HIV prevention services, such as pre-exposure prophylaxis (PrEP), remains low. This systematic review summarizes...

Promoting healthy aging through mindfulness and yoga: A systematic review of interventions for people living with HIV who use drugs or who have a history of substance use

2025

Advances in HIV care and broader access to antiretroviral therapy (ART) have extended life expectancy for people living with HIV, yet aging-related health concerns, especially among those who use substances,...

Human milk oligosaccharides, microbiome, antiretroviral therapy and HIV infected mothers: Reasons to still promote breastfeeding in HIV context of lactating countries, a mini-narrative review

2025

Breastfeeding is the preferred feeding for newborns during the first 6 months of life and until the age of 2 years or beyond. The benefits of breastfeeding remain significant, even in cases...

Effectiveness of mobile health (mHealth) interventions on ART adherence among people living with HIV in low- and middle-income countries: a systematic review and meta-analysis

2025

Antiretroviral therapy (ART) is essential for HIV treatment, yet maintaining high adherence remains challenging in resource-limited settings. Mobile health (mHealth) interventions offer a scalable approach to support adherence. This meta-analysis...

Community-based interventions against HIV-related stigma: A systematic review of evidence in Sub-Saharan Africa

2025

Background: HIV-related stigma remains a key barrier to the attainment of the UNAIDS global goal of ending AIDS by 2030. Due to the social and contextual nature of HIV-related stigma, community-based...

Effect of human immunodeficiency virus on lung function and structure: A systematic review and meta-analysis

2025

Rationale: Obstructive lung disease (OLD) pathogenesis includes inhalational (e.g., smoking) and noninhalational mechanisms (e.g., infections). Human immunodeficiency virus (HIV) has been suggested as a novel OLD risk factor. Substantial data...

The prevalence of nonalcoholic fatty liver disease in people living with HIV: A systematic review and meta-analysis

2025

Background: Owing to long-term antiretroviral therapy (ART), the incidence of non-HIV-related chronic diseases is increasing, and liver disease is the leading cause of increased AIDS mortality. Moreover, the prevalence of NAFLD...

Comprehensive appraisal of the association between sexually transmitted infections and prostate cancer: A scoping review of empirical studies, reviews, and meta-analyses

2025

We performed a scoping review on the association of sexually transmitted infections (STIs) with prostate cancer and identified knowledge gaps. Searching four databases (Medline, Embase, Scopus, and Cochrane) identified 286...

Four decades of overdose prevention centres: Lessons for the future from a realist review

2025

BACKGROUND: Overdose prevention centres (OPCs) are spaces where people can consume previously obtained illicit drugs under the supervision of staff who can intervene to prevent and manage overdose.AÿThey have been...

Improving communication: A narrative synthesis of interventions for HIV disclosure to pediatric populations

2025

PURPOSE OF REVIEW: HIV remains a significant global public health concern, affecting millions worldwide, including children. Disclosure of HIV status to infected children holds several benefits, yet rates of disclosure...

Technologies for healthy lifestyle in people with HIV: A systematic review

2025

OBJECTIVE: to analyze clinical trials that assessed the effectiveness of technologies for healthy lifestyles in people with HIV. METHOD: A systematic review, conducted in five databases, with association of controlled...

Sexually transmitted and blood-borne infections in transgender and non-binary people in Canada: A scoping review

2025

In the 2021 census, 100,815 people in Canada aged 15 and older identified as transgender or non-binary. Globally, transgender people are disproportionately burdened by several Sexually Transmitted and Blood-Borne Infections...

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