SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Global and regional epidemiology of HIV-1 recombinants in 1990-2015: A systematic review and global survey

2019

Background: Global genetic diversity of HIV-1 is a major challenge to the development of HIV vaccines. We aimed to estimate the regional and global distribution of HIV-1 subtypes and recombinants...

A qualitative systematic review of cigarette smoking cessation interventions for persons living with HIV

2019

Persons living with HIV (PLWH) have disproportionately high rates of both cigarette smoking and tobacco-induced negative health outcomes. The goal of this qualitative systematic review was to identify gaps in...

Factors associated with antiretroviral therapy adherence in adults: An integrative review of literature

2019

AIDS is an advanced clinical manifestation of HIV infection. It generates severe immunodeficiency and associated infections that may lead to death. The antiretroviral therapy (ART) has reduced the morbimortality of...

Gender-based violence and engagement in biomedical HIV prevention, care and treatment: A scoping review

2019

BACKGROUND: While gender-based violence (GBV) has been shown to increase women’s risk of HIV acquisition, the role of GBV in the HIV testing to care continuum is less clear. Clarifying...

Dolutegravir based antiretroviral therapy compared to other combined antiretroviral regimens for the treatment of HIV-infected naive patients: A systematic review and meta-analysis

2019

BACKGROUND: Numerous randomized clinical trials (RCTs) were conducted to evaluate dolutegravir based triple antiretroviral therapy (ART) compared to other triple antiretroviral regimens in naive patients, and a summary of the...

Use of an indeterminate range in HIV early infant diagnosis: A systematic review and meta-analysis

2019

BACKGROUND: Expanded access to HIV antiretrovirals has dramatically reduced mother-to-child transmission of HIV. However, there is increasing concern around false-positive HIV test results in perinatally HIV-exposed infants but few insights...

Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: A systematic review and meta-analysis

2019

BACKGROUND: Blood transfusion is one of the routine therapeutic interventions in hospitals that can be lifesaving. However, this intervention is related to several transfusion-related infections. The human immunodeficiency virus (HIV)...

Interventions to improve linkage to HIV care in the era of “treat all” in sub-Saharan Africa: A systematic review

2019

PURPOSE OF THE REVIEW: In 2015, antiretroviral therapy (ART) was recommended for all people living with HIV (PLHIV) regardless of CD4 count (“Treat All”). To better understand how to improve...

Can mental health treatments help prevent or reduce intimate partner violence in low- and middle-income countries? A systematic review

2019

BACKGROUND: Epidemiological research suggests an interrelationship between mental health problems and the (re)occurrence of intimate partner violence (IPV). However, little is known about the impact of mental health treatments on...

Healthcare workers’ perspectives on the barriers to providing HIV services to children in sub-Saharan Africa

2019

Background: In order to accelerate the HIV response to meet the UNAIDS 90-90-90 indicators for children, healthcare workers need to lead a scale-up of HIV services in primary healthcare settings....

HIV prevention cascade theory and its relation to social dimensions of health: A case for Nigeria

2019

Background: Nigeria has the second largest HIV epidemic in the world and one of the highest rates of new infection in sub-Saharan Africa. Within the last three decades, majority of...

HIV non-occupational post exposure prophylaxis in Nigeria: A systematic review of research evidence and practice

2019

Background: Although non-occupational Human Immunodeficiency Virus (HIV) post-exposure prophylaxis (nPEP) has been proven to be efficacious in preventing HIV, it remains an underutilized prevention strategy in Nigeria. We aimed to...

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