SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Analysis of systematic reviews of medication adherence interventions for persons with HIV, 1996–2017

2019

This overview of reviews summarizes the evidence from systematic reviews (SR) on the effectiveness of antiretroviral therapy (ART) adherence interventions for people with HIV (PWH) and descriptively compares adherence interventions...

Screening tools for HIV-associated neurocognitive disorders among adults living with HIV in sub-Saharan Africa: A scoping review

2019

Background: People living with HIV are at risk of developing HIV-associated neurocognitive disorders (HAND) which adversely affects their quality of life. Routine screening of HAND in HIV care is recommended...

The risk of coercion in the context of HIV self-testing

2019

Key take-home messages While studies to date indicate that there are many benefits of HIV self-testing (also known as home-testing) and the risk of harm through coerced self-testing is minimal,...

Voluntary medical male circumcision and HIV infection among men who have sex with men: Implications from a systematic review

2019

Background: With the rapidly-increased HIV epidemic among men who have sex with men worldwide, the effectiveness of voluntary medical male circumcision as the tool of HIV prevention still remains undetermined....

Immunological efficacy of Tenofovir disproxil fumarate-containing regimens in Patients With HIV-HBV coinfection: A systematic review and meta-analysis

2019

Background: Hepatitis B virus (HBV) coinfection is common in HIV-positive patients. HIV infection modifies the natural course of HBV infection, leading to a faster progression of liver-related morbidity and mortality...

Are policy initiatives aligned to meet UNAIDS 90-90-90 targets impacting HIV testing and linkages to care? Evidence from a systematic review

2019

Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) Fast-Track initiative seeks to eliminate AIDS as a health threat by 2030, with its focus on UNAIDS 90-90-90 targets. Effective policies and...

Guides concerning tenofovir exposure via breastfeeding: A comparison of drug dosages by developmental stage

2019

Tenofovir disoproxil fumarate (TDF) is a prodrug of tenofovir, and after being administrated orally, it converts to tenofovir in the blood. With the increasing use of TDF in women for...

Microfinance interventions and HIV treatment outcomes: A synthesizing conceptual framework and systematic review

2019

BACKGROUND: Microfinance interventions have the potential to improve HIV treatment outcomes, but the mechanisms through which they operate are not entirely clear. OBJECTIVES: To construct a synthesizing conceptual framework for...

Association between the UGT1A1*28 allele and hyperbilirubinemia in HIV-positive patients receiving atazanavir: A meta-analysis

2019

OBJECTIVES: The UGT1A1*28 allele in HIV-positive patients receiving atazanavir(ATV) might be associated with the risk of hyperbilirubinemia. Owing to mixed and inconclusive results, a meta-analysis was conducted to systematically summarize...

Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: Individual patient data meta-analysis

2019

BACKGROUND: Xpert MTB/RIF, the most widely used automated nucleic acid amplification test for tuberculosis, is available in more than 130 countries. Although diagnostic accuracy is well documented, anticipated improvements in...

HIV epidemiology among female sex workers and their clients in the Middle East and North Africa: Systematic review, meta-analyses, and meta-regressions

2019

BACKGROUND: HIV epidemiology among female sex workers (FSWs) and their clients in the Middle East and North Africa (MENA) region is poorly understood. We addressed this gap through a comprehensive...

Effects of psychosocial interventions on children affected by parental HIV/AIDS: A meta-analysis on depression and anxiety

2019

BACKGROUND: Children orphaned by parental AIDS or those of parents with HIV infection demonstrate many negative mental health outcomes. Different types of psychosocial interventions have been conducted to improve the...

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