SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV

2018

Key take-home messages Oral PrEP (tenofovir disoproxil fumarate with emtricitabine) is highly protective against HIV acquisition across various populations and across different dosing schedules. Open label and demonstration projects in...

A review of long-term toxicity of antiretroviral treatment regimens and implications for an aging population

2018

Human immunodeficiency virus (HIV) is a chronic infectious disease currently requiring lifelong antiretroviral therapy (ART). People living with HIV (PLWH) face an increased risk of comorbidities associated with aging, chronic...

Is UNAIDS 90-90-90 target a dream or a reality for Middle East and North Africa region on ending the AIDS epidemic? A review study

2018

Middle East and North Africa (MENA) region is lagging far behind the global average to reach 90-90-90 targets. This study uses the UNAIDS 90-90-90 program to evaluate the HIV current...

Role of SDF-1 3’A polymorphism in HIV-1 disease progression: A systematic review and meta-analysis

2018

BACKGROUND: Chemokine stromal cell-derived factor 1(SDF-1) 3’A polymorphism has been reported to influence HIV-1 disease pathogenesis and progression, but the results remain controversial. OBJECTIVES: A meta-analysis was carried out to...

Sustained virological response in special populations with chronic hepatitis C using interferon-free treatments: A systematic review and meta-analysis of observational cohort studies

2018

BACKGROUND AND OBJECTIVES: Hepatitis C treatment has changed considerably in recent years, and many interferon (IFN)-free therapies are now available. Considering the high rates of sustained virological response (SVR) presented...

A scoping review of photovoice research among people with HIV

2018

We describe how Photovoice-a participatory method in which people express and share ideas via images-has been used in research with people living with HIV (PLWH). Four databases, reference lists, and...

A meta-analysis of HIV postexposure prophylaxis among sexually assaulted patients in the United States

2018

Sexual assault (SA) is a major public health problem that leaves patients at risk for HIV. The gold standard of medical treatment for SA patients includes prophylactic treatment to prevent...

Do you PrEP? A review of primary care provider knowledge of PrEP and attitudes on prescribing PrEP

2018

Oral preexposure prophylaxis (PrEP) has been proven to be a safe and effective means of preventing HIV. The purpose of our literature review was to examine primary care provider knowledge...

Postpartum women living with HIV: Challenges related to retention in care, treatment adherence, and mental health

2018

Key take-home messages Postpartum women living with HIV may find it challenging to remain engaged in HIV care and achieve optimal adherence to antiretroviral medications. Late entry or suboptimal engagement...

Integration of neonatal and child health interventions with pediatric HIV interventions in global health

2018

Background/Objectives: In the last decade, many strategies have called for integration of HIV and child survival platforms to reduce missed opportunities and improve child health outcomes. Countries with generalized HIV...

HIV serostatus disclosure in the Democratic Republic of the Congo: A systematic review

2018

HIV status disclosure among people living with HIV/AIDS has been shown to have a number of both personal and public health benefits, but rates of HIV status disclosure remain low...

Posttraumatic growth among people living with HIV: A systematic review

2018

OBJECTIVES: The aim of this systematic review was to analyse, synthesise and review existing results on posttraumatic growth (PTG) among PLWH. In particular, we investigated the relationship of PTG with...

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