SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Efficacy and safety of raltegravir-based dual therapy in AIDS patients: A meta-analysis of randomized controlled trials

2019

Background: The life expectancy for HIV-infected individuals has improved dramatically because of improvements in antiretroviral therapy (ART). Today, a simplified two-drug regimen enhances adherence and treatment satisfaction by reducing adverse...

Strategies to improve linkage to HIV care in urban areas of sub-Saharan Africa: A systematic review

2019

Of the 37 million people estimated to be living with HIV globally in 2017, about 24.7 million were in the sub-Saharan Africa region, which has been and remains worst affected...

Treatment outcomes and antiretroviral uptake in multidrug-resistant tuberculosis and HIV co-infected patients in sub Saharan Africa: A systematic review and meta-analysis

2019

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) in HIV endemic settings is a major threat to public health. MDR-TB is a substantial and underreported problem in Sub-Saharan Africa (SSA), with recognised cases projected...

Safety and efficacy of human papillomavirus vaccination for people living with HIV: A systematic review and meta-analysis

2019

No abstract available

Providing competent, comprehensive and inclusive sexual health services for men who have sex with men in low- and middle-income countries: A scoping review

2019

Although men who have sex with men (MSM) are disproportionately affected by HIV and other sexually transmissible infections, sexual health services for MSM in low- and middle-income countries (LMIC) remain...

Risk factors for prescription drug diversion among people living with HIV: A systematic scoping review

2019

BACKGROUND: In addition to numerous infections and frequent pain constantly affecting people living with HIV (PLWH), various risk factors might contribute to prescription drug diversion. The purpose of the study...

The effectiveness of demand creation interventions for voluntary male medical circumcision for HIV prevention in sub-Saharan Africa: A mixed methods systematic review

2019

INTRODUCTION: UNAIDS has recommended that in 14 countries across sub-Saharan Africa (SSA), 90% of men aged 10 to 29 years should be circumcised by 2021 to help reduce transmission of...

A systematic review of multi-level stigma interventions: State of the science and future directions

2019

BACKGROUND: Researchers have long recognized that stigma is a global, multi-level phenomenon requiring intervention approaches that target multiple levels including individual, interpersonal, community, and structural levels. While existing interventions have...

Strength-based interventions for HIV prevention and sexual risk reduction among girls and young women: A resilience-focused systematic review

2019

Despite significant public health efforts, girls and young women still face gender-specific barriers to achieving optimal physical and mental health. Public health interventions have historically addressed the health needs of...

The willingness to participate in biomedical research involving human beings in low- and middle-income countries: A systematic review

2019

OBJECTIVES: To systematically review reasons for the willingness to participate in biomedical human subjects research in low- and middle-income countries (LMICs). METHODS: Five databases were systematically searched for articles published...

Cancer disparities in people with HIV: A systematic review of screening for non-AIDS-defining malignancies

2019

BACKGROUND: People with HIV (PWHIV) have improved survival because of the advent of antiretroviral therapy. Consequently, PWHIV experience higher rates of non-acquired immunodeficiency syndrome-defining malignancies (NADMs). Previous studies have demonstrated...

Cost of differentiated HIV antiretroviral therapy delivery strategies in sub-Saharan Africa: A systematic review

2019

BACKGROUND: Efficient and scalable models for HIV treatment are needed to maximize health outcomes with available resources. By adapting services to client needs, differentiated antiretroviral therapy (DART) has the potential...

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