SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV testing strategies employed in health care settings in the European Union/European Economic Area (EU/EEA): Evidence from a systematic review

2019

OBJECTIVES: Despite the availability of HIV testing guidelines to facilitate prompt diagnosis, late HIV diagnosis remains high across Europe. The study synthesizes recent evidence on HIV testing strategies adopted in...

Global epidemiologic characteristics of sexually transmitted infections among individuals using preexposure prophylaxis for the prevention of HIV infection: A systematic review and meta-analysis

2019

Importance: Despite a global increase in sexually transmitted infections (STIs), there is limited focus and investment in STI management within HIV programs, in which risks for STIs are likely to...

Views of service providers and adolescents on use of sexual and reproductive health services by adolescents: A systematic review

2019

This review examines the literature on adolescents’ and providers’ views on access and use of Sexual and Reproductive Health (SRH) information and services. The SRH services referred to in this...

Sexualized drug use (chemsex and methamphetamine) and men who have sex with men

2019

Key take-home messages Chemsex and methamphetamine use are associated with sexual health-related harms among men who have sex with men. Methamphetamine is the most commonly reported drug in sexualized drug...

Systematic review of cognitive behavior therapy to improve mental health of women living with HIV

2019

Psychological distress is highly prevalent in people living with HIV. Cognitive behavior therapy (CBT) has been associated with improved mental health outcomes in HIV-infected men who have sex with men...

Behavioral economic insights to improve medication adherence in adults with chronic conditions: A scoping review

2019

Objective: The objective of this review is to map the evidence on the use of behavioral economic insights to improve medication adherence in adults with chronic conditions. Introduction: Medication non-adherence is a...

Antiretroviral implants for treatment and prevention of HIV infection

2018

PURPOSE OF REVIEW: Poor adherence to oral antiretroviral formulations remains the major barrier to the success of long-term treatment and prevention strategies. Although a number of approaches have been developed...

Estimating the prevalence of HIV and sexual behaviors among the US transgender population: A review and meta-analysis, 2006-2017

2018

BACKGROUND: Transgender women (transwomen) in the United States have been shown to have high HIV risk with Black and Hispanic transwomen being particularly vulnerable. Growing research on transgender men (transmen)...

Stroke in human immunodeficiency virus-infected individuals in Sub-Saharan Africa (SSA): A systematic review

2018

BACKGROUND: Human immunodeficiency virus (HIV) infection is associated with worse outcomes after stroke, but this association is less well-described in sub-Saharan Africa (SSA). We reviewed literature on stroke among people...

Type-specific anal human papillomavirus prevalence among men, according to sexual preference and HIV status: A systematic literature review and meta-analysis

2018

Background: Anal human papillomavirus (HPV) infection, most notably of HPV16, the central cause of anal cancer, is increased by anal sexual intercourse and worsened by HIV-positivity. Methods: We undertook a...

Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV

2018

Key take-home messages Oral PrEP (tenofovir disoproxil fumarate with emtricitabine) is highly protective against HIV acquisition across various populations and across different dosing schedules. Open label and demonstration projects in...

A review of long-term toxicity of antiretroviral treatment regimens and implications for an aging population

2018

Human immunodeficiency virus (HIV) is a chronic infectious disease currently requiring lifelong antiretroviral therapy (ART). People living with HIV (PLWH) face an increased risk of comorbidities associated with aging, chronic...

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