SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

(1) Background: Second-generation integrase strand transfer inhibitors (INSTIs) are now the preferred first-line therapies for human immunodeficiency virus (HIV). However, concerns regarding their side effects, such as weight gain and...

BACKGROUND: Adolescents and young adults (AYA) are disproportionately affected by human immunodeficiency virus (HIV) globally, with high-burden population subgroups differing across regions. Cost-effectiveness modeling analyses of AYA-focused HIV interventions have...

BackgroundHepatitis C virus (HCV) coinfection is common among people living with HIV (PLWH) and is associated with adverse outcomes. However, the specific association between HCV coinfection and the risk of...

Introduction Pneumocystis pneumonia (PCP) is a life-threatening infection in both HIV- infected and non-HIV-infected immunocompromised patients. Although Trimethoprim-Sulfamethoxazole (TMP/SMX) combined with echinocandins has been used clinically, whether this combination is...

Introduction The greatest burden of HIV infection is in sub-Saharan African countries. The burden of treatment failure among children living with HIV remains significantly high due to delayed diagnosis and...

Background Interventions involving Mobile Health (mHealth) have shown promise to improve retention in care and adherence to antiretroviral therapy (ART) among pregnant or breastfeeding women living with HIV (PBWLH). However,...

BACKGROUND: HIV and tuberculosis (TB) co-infection poses a significant health challenge, particularly when involving the central nervous system (CNS), where it leads to severe morbidity and mortality. Current treatments face...

Objective: Increasingly, pregnant women with HIV (WHIV) initiate antiretroviral therapy (ART) before conception. We assessed the risk of adverse perinatal outcomes among pregnant WHIV initiating ART preconception or antenatally, compared with...

OBJECTIVES: People living with HIV (PLWH) were previously shown to have a higher prevalence of non-calcified coronary plaque with discrepant results for coronary stenosis and any plaque prevalence. This systematic...

Papillomaviruses are double-stranded DNA viruses, and it is essential to clarify their genotypic distribution for their effective prevention and clinical management. In this study, we aimed to evaluate the prevalence...

PURPOSE OF REVIEW: Chronic pain affects 25-85% of people living with HIV (PLWH), negatively impacting health behaviors and HIV health outcomes. While opioids are frequently prescribed for pain, there are...

Homelessness is a global problem with wide-ranging causes and contexts. People experiencing homelessness and unstable housing (HUH) are disproportionately affected by HIV and face worse treatment outcomes than those with...