SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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NARCAN® Nasal Spray efficacy for emergency treatment of opioid overdose

2018

Key take-home messages The administration of ready-to-use, needle-free concentrated NARCAN® Nasal Spray (containing 4mg of naloxone hydrochloride in low volume of 0.1 mL) results in pharmacokinetic parameters that either equal...

The state of adherence to HIV care in black women

2018

The purpose of this systematic review was to assess the state of adherence to HIV care such as HIV medication and appointment adherence among Black women in the United States....

Medication adherence in pregnant women with human immunodeficiency virus receiving antiretroviral therapy in sub-Saharan Africa: A systematic review

2018

BACKGROUND: The use of antiretroviral therapy (ART) is a core strategy proposed by the World Health Organization in preventing mother to child transmission (MTCT) of HIV. This systematic review aimed...

Analytical quality and effectiveness of point-of-care testing in community pharmacies: A systematic literature review

2018

BACKGROUND: Point-of-care tests are characterised through the ability of conducting them near the patient’s side without the necessity of a laboratory. They can be applied in different healthcare settings to...

Dolutegravir dual therapy as maintenance Treatment in HIV-infected Patients: A review

2018

OBJECTIVE: To review available evidence for dolutegravir-based dual therapy as maintenance treatment in HIV-1 infected patients. DATA SOURCES: A literature search was conducted using PubMed, MEDLINE, and Google Scholar to...

Efficacy and safety of boosted darunavir-based antiretroviral therapy in HIV-1-positive patients: Results from a meta-analysis of clinical trials

2018

Darunavir/ritonavir (DRV/r) is a second-generation protease inhibitor used in treatment-naive and -experienced HIV-positive adult patients. To evaluate efficacy and safety in these patient settings, we performed a meta-analysis of randomized...

Cost-effectiveness of HIV screening in high-income countries: A systematic review

2018

INTRODUCTION: Over 2 million people in high-income countries live with HIV. Early diagnosis and treatment present benefits for infected subjects and reduce secondary transmissions. Cost-effectiveness analyses are important to effectively...

STI health disparities: A systematic review and meta-analysis of the effectiveness of preventive interventions in educational settings

2018

The purpose of this systematic review and meta-analysis was to address disparities related to sexual health among students by examining the effectiveness of sexually transmitted infection (STI) preventive interventions in...

Epidemiology of depressive disorders in people living with HIV in Africa: A systematic review and meta-analysis: Burden of depression in HIV in Africa

2018

OBJECTIVE: The burden of HIV infection is higher in Africa where 70% of people living with HIV (PLHIV) resides. Since depression can negatively impact the course of HIV infection, it...

Psychosocial factors associated with persistent pain in people with HIV: A systematic review with meta-analysis

2018

Chronic pain remains a prevalent and disabling problem for people living with the human immunodeficiency virus (HIV) in the current antiretroviral (ART) treatment era. Psychosocial treatments may have promise for...

Global research output on HIV/AIDS-related medication adherence from 1980 to 2017

2018

BACKGROUND: Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) are global health burden. Medication adherence in people living with HIV (PLWH) is a key element in reducing morbidity and...

Influenza vaccination for HIV-positive people: Systematic review and network meta-analysis

2018

BACKGROUND: People with Human Immunodeficiency Virus (HIV) are highly susceptible to influenza-related morbidity and mortality. In order to assess comparative efficacy of influenza vaccine strategies among HIV-positive people, we performed...

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