SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV risk reduction interventions among substance-abusing reproductive-age women: A systematic review

2017

HIV/AIDS is one of the leading causes of death among reproductive-age women throughout the world, and substance abuse plays a major role in HIV infection. We conducted a systematic review,...

Optimal anti-retroviral prophylaxis in infants at high-risk of acquiring human immunodeficiency virus: A systematic review

2017

INTRODUCTION: The risk of perinatal HIV infection can be dramatically reduced through maternal antiretroviral therapy (ART) and infant antiretroviral (ARV) postnatal prophylaxis. The 2013 WHO guidelines recommended four to six...

Effectiveness of peer-led interventions to increase HIV testing among men who have sex with men: A systematic review and meta-analysis

2017

HIV testing constitutes a key step along the continuum of HIV care. Men who have sex with men (MSM) have low HIV testing rates and delayed diagnosis, especially in low-resource...

Efficacy and safety of atazanavir/ritonavir-based antiretroviral therapy for HIV-1 infected subjects: A systematic review and meta-analysis

2017

Atazanavir (ATZ) is a well-tolerated protease inhibitor that can be boosted with ritonavir (r) to treat infection with resistant strains of human immunodeficiency virus 1 (HIV-1). The aim of this...

The impact of programs for prevention of mother-to-child transmission of HIV on health care services and systems in sub-Saharan Africa – A review

2017

Background: The global scale-up of Prevention of mother-to-child transmission (PMTCT) services is credited for a 52% worldwide decline in new HIV infections among children between 2001 and 2012. However, the...

It’s not just the pills: A qualitative meta-synthesis of HIV antiretroviral adherence research

2017

Antiretroviral therapy (ART) improves the health and longevity of people living with HIV infection (PLWH) and also prevents transmission of the virus. Yet, lack of adherence to ART regimens has...

Can self-testing increase HIV testing among men who have sex with men: A systematic review and meta-analysis

2017

BACKGROUND: Globally, four out of ten individuals living with HIV have not been tested for HIV. Testing is especially important for men who have sex with men (MSM), among whom...

Association between medication regimen complexity and pharmacotherapy adherence: A systematic review

2017

PURPOSE: The purpose of this study was to systematically review evidence regarding the association between regimen complexity and adherence. METHODS: Articles were searched in MEDLINE, LILACS, Cochrane, CINAHL, PsycINFO and...

Where is the evidence? The use of routinely-collected patient data to retain adults on antiretroviral treatment in low and middle income countries-a state of the evidence review

2017

Retention rates in antiretroviral treatment (ART) in low- and middle-income countries are suboptimal for meeting global “90-90-90” treatment targets. Interventions using routinely collected patient data to follow up with ART...

Atypical presentations of cutaneous leishmaniasis: A systematic review

2017

Cutaneous Leishmaniasis (CL) is endemic in 88 countries, showing relevant prevalences. The aim of this study was to perform a systematic review on atypical lesions of CL around the world,...

Efficacy and tolerability of tenofovir disoproxil fumarate based regimen as compared to zidovudine based regimens: A systematic review and meta-analysis

2017

BACKGROUND: Although tenofovir (TDF)/emtricitabine (FTC)/efavirenz (EFV) and zidovudine (ZDV)/lamivudine (3TC)/efavirenz (EFV) are used as preferred first line regimen, their head-to-head comparison in terms of their efficacy and tolerability was limited....

Healthy aging in older women living with HIV infection: A systematic review of psychosocial factors

2017

Due to life-enhancing effects of antiretroviral therapy, HIV-positive persons have the potential for long life comparable to their uninfected peers. Older women (age 50+) living with HIV (OWLH) are often...

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