SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

ABSTRACT Human Immunodeficiency Virus (HIV) infection is stigmatizing, especially for key populations, who are disproportionately affected by Sexually Transmitted Infections (STIs). The stigma and discrimination suffered by these groups are...

Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...

OBJECTIVE: To review the efficacy and safety of lenacapavir for the prevention of HIV-1 infection. DATA SOURCES: Clinical trials and review articles were obtained through August 2025 using search terms...

Effective antiretroviral therapy has extended the life expectancy of people living with HIV and in Western countries, with 50% of individuals in Western countries now aged 50 or older. The...

Human immunodeficiency virus (HIV) remains a public health issue in the U.S., affecting approximately 1.2 million individuals, many of whom are unaware of their infection status. This study reviews predictors...

BACKGROUND: Cyclospora cayetanensis is a coccidian protozoan parasite belonging to the phylum Apicomplexa. This systematic review and meta-analysis aimed to assess the prevalence and risk factors of C. cayetanensis in...

Transgender individuals, whose gender identity differs from their assigned sex at birth, often undergo pharmacotherapy, including hormone therapy (HT), as part of their gender-affirming care. This pharmacotherapy, particularly when combined...

INTRODUCTION: Black/African American men who have sex with other men (BMSM) are disproportionately affected by HIV, experience significant disparities in HIV incidence, and face significant barriers to accessing HIV treatment...

Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...

Objectives: The objective of this review was to assess the effectiveness of HIVST in terms of increasing HIV testing, early detection of HIV, and sexually transmitted infections among MSM via...

Purpose Minority stress theory posits health disparities among sexual minority men (SMM; i.e., non-heterosexual) result from experiences of sexual minority stigma (SMS). This systematic review synthesizes quantitative findings on the...

BACKGROUND: Viral rebound (VR), the resurgence of detectable human immunodeficiency virus (HIV) viral loads (> 50 copies/mL) after suppression, remains a challenge for individuals on antiretroviral therapy (ART) in South...