SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Human infectious diseases and risk of preeclampsia: An updated review of the literature

2017

BACKGROUND: Preeclampsia (PE) is one of the major causes of maternal and perinatal morbidity and mortality, especially in low- and middle-income countries. In recent years, a growing body of literatures...

Integrating cervical cancer with HIV healthcare services: A systematic review

2017

BACKGROUND: Cervical cancer is a major public health problem. Even though readily preventable, it is the fourth leading cause of death in women globally. Women living with HIV are at...

Factors associated with HIV testing and HIV treatment adherence: A systematic review

2017

BACKGROUND: The impact of the global economic crisis on HIV-related access and care remains unclear. The objective of this systematic review of the literature was to evaluate the association between...

Behavioural disinhibition in the general population during the antiretroviral therapy roll-out in Sub-Saharan Africa: Systematic review and meta-analysis

2017

Objectives: Improved life expectancy and reduced transmission probabilities due to ART may result in behavioural disinhibition – that is an increase in sexual risk behaviour in response to a perceived lower...

Interventions to improve adherence to antiretroviral therapy: A systematic review and network meta-analysis

2017

BACKGROUND: High adherence to antiretroviral therapy is crucial to the success of HIV treatment. We evaluated comparative effectiveness of adherence interventions with the aim of informing the WHO’s global guidance...

Association between HIV infection and prevalence of erectile dysfunction: A systematic review and meta-analysis

2017

BACKGROUND: The prevalence of erectile dysfunction (ED) in men positive for HIV has been reported to exceed the baseline of the general population. However, no meta-analysis or conclusive review has...

Prevalence of depression in people with HIV and AIDS in Iran: A systematic review

2017

Background: Depression is the most common mental disorder in individuals with HIV and AIDS (PLWHA), and comorbidity with depression exacerbates the disease. Several studies have estimated the prevalence of depression...

Pharmacokinetics of efavirenz in patients on antituberculosis treatment in high HIV and tuberculosis burden countries: A systematic review

2017

AIMS: Efavirenz (EFV) and Rifampicin-Isoniazid (RH) are cornerstone drugs in HIV-tuberculosis (TB) co-infection treatment but with complex drug interactions, efficacy and safety challenges. We reviewed recent data on EFV and...

Health literacy for people living with HIV/Aids: An integrative review

2017

Objective:: to analyze knowledge produced by research about health literacy for adult with HIV/Aids. Method:: an integrative literature review, using six databases, was conducted between January and April of 2014....

Effect of probiotic supplementation on CD4 cell count in HIV-infected patients: A systematic review and meta-analysis

2017

Progressive decline in CD4 cell counts is associated with human immunodeficiency virus (HIV) disease progression. Loss of CD4 cells might contribute to gut microbiota alteration and bacterial translocation. Probiotics, by...

A systematic review of palliative care intervention outcomes and outcome measures in low resource countries

2017

CONTEXT: To meet the growing need for palliative care in low-resource countries, palliative care programs should be evidence-based and contextually appropriate. This study was conducted to synthesize the current evidence...

Does pre-exposure prophylaxis (PrEP) for HIV prevention in men who have sex with men (MSM) change risk behavior? A systematic review

2017

BACKGROUND: Pre-exposure prophylaxis (PrEP) for HIV has been available since 2012. Even so, PrEP has not been widely accepted among healthcare providers and MSM some of whom are convinced that...

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