SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Opportunities and gaps in primary care preventative health services for transgender patients: A systemic review

2017

Purpose: Transgender people face barriers to accessing healthcare, resulting in population-level disparities in health outcomes. Little research is available to better understand the receipt of primary healthcare among transgender patients...

Prevalence of Kaposi’s sarcoma-associated herpesvirus among intravenous drug users: A systematic review and meta-analysis

2017

Intravenous drug users (IDUs) have been demonstrated to be highly vulnerable to HIV/AIDS. Nevertheless, the prevalence of Kaposi’s sarcoma associated herpesvirus (KSHV), an important co-infected agent with HIV, among this...

Status and methodology of publicly available national HIV care continua and 90-90-90 targets: A systematic review

2017

BACKGROUND: In 2014, the Joint United Nations Program on HIV/AIDS (UNAIDS) issued treatment goals for human immunodeficiency virus (HIV). The 90-90-90 target specifies that by 2020, 90% of individuals living...

Is salivary IgA level a potential biomarker for immunosuppression in HIV-positive children? A systematic review and meta-analysis

2017

The aim of this systematic review was to determine whether or not assessment of salivary secretory immunoglobulin A (sIgA) levels could be a potential biomarker for immunosuppression in HIV-positive children....

Awareness and willingness to use HIV pre-exposure prophylaxis among men who have sex with men in low- and middle-income countries: A systematic review and meta-analysis

2017

INTRODUCTION: To facilitate provision of pre-exposure prophylaxis (PrEP) in low- and middle-income countries (LMIC), a better understanding of potential demand and user preferences is required. This review assessed awareness and...

Pneumococcal conjugate vaccine in HIV-infected and HIV-exposed, uninfected children

2017

INTRODUCTION: Incidence of invasive pneumococcal disease (IPD) among HIV-infected children is 20-40 fold greater compared to HIV-uninfected children, including among HIV-infected children on antiretroviral therapy (ART). Also, HIV-exposed, uninfected children...

Review of cytomegalovirus coinfection in HIV-infected individuals in Africa

2017

BACKGROUND: Cytomegalovirus (CMV) infection among HIV-infected individuals may cause end-organ disease, which is an AIDS-defining condition. Evidence from high-income countries suggests that CMV may alter the outcome of HIV infection,...

Free software to analyse the clinical relevance of drug interactions with antiretroviral agents (SIMARV((R))) in patients with HIV/AIDS

2017

BACKGROUND: Highly active antiretroviral therapy has extended the expected lifespan of patients with HIV/AIDS. However, the therapeutic benefits of some drugs used simultaneously with highly active antiretroviral therapy may be...

Retention in HIV care during pregnancy and the postpartum period in the option B+ era: A systematic review and meta-analysis of studies in Africa

2017

BACKGROUND: Under Option B+ guidelines for prevention of mother-to-child transmission of HIV (PMTCT), pregnant and breastfeeding women initiate antiretroviral therapy (ART) for lifelong use. The objectives of this study were:...

Effect of frequency of clinic visits and medication pick-up on antiretroviral treatment outcomes: A systematic literature review and meta-analysis

2017

INTRODUCTION: Expanding and sustaining antiretroviral therapy (ART) coverage may require simplified HIV service delivery strategies that concomitantly reduce the burden of care on the health system and patients while ensuring...

Systematic review: A review of adolescent behavior change interventions [BCI] and their effectiveness in HIV and AIDS prevention in sub-Saharan Africa

2017

BACKGROUND: Despite sub-Saharan Africa [SSA] constituting just 12% of the world’s population, the region has the highest burden of HIV with 70% of HIV infection in general and 80% of...

A twenty-first-century perspective of disseminated histoplasmosis in India: Literature review and retrospective analysis of published and unpublished cases at a tertiary care hospital in North India

2017

PURPOSE: Published literature lacks systematic studies on disseminated histoplasmosis in India, and previous reviews on its epidemiology in India were conducted two decades back. Thus, we review the Indian studies...

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