SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Obstructive lung diseases in HIV: A clinical review and identification of key future research needs

2017

HIV infection has shifted from what was once a disease directly impacting short-term mortality to what is now a chronic illness controllable in the era of effective combination antiretroviral therapy...

Effect of secondary preventive therapy on recurrence of tuberculosis in HIV-infected individuals: A systematic review

2017

Human immunodeficiency virus (HIV)-infected individuals successfully treated for tuberculosis (TB) remain at risk of recurrence of the disease, especially in high TB incidence settings. We performed a systematic review, investigating...

The HIV-1 vpr protein: A multifaceted target for therapeutic intervention

2017

The human immunodeficiency virus type 1 (HIV-1) Vpr protein is an attractive target for antiretroviral drug development. The conservation both of the structure along virus evolution and the amino acid...

Criminalization of HIV exposure: A review of empirical studies in the United States

2017

This review of literature identifies and describes US empirical studies on the criminalization of HIV exposure, examines findings on key questions about these laws, highlights knowledge gaps, and sets a...

HIV risk inside U.S. prisons: A systematic review of risk reduction interventions conducted in U.S. prisons

2017

HIV prevalence in correctional populations is approximately five times that of the general adult population. This systematic review examines the broad question of HIV prevention and interventions to reduce inmate...

Diabetes, metabolic syndrome and dyslipidemia in people living with HIV in Africa: Re-emerging challenges not to be forgotten

2017

Background: The current challenge in managing people living with human immunodeficiency virus (PLWHIV) includes the identification and monitoring for comorbid health risks associated with HIV and its treatment and longer...

mHealth interventions to support self-management in HIV: A systematic review

2017

Background: Self-management is an important aspect of long-term HIV treatment. Mobile technologies offer the potential to efficiently deliver interventions to facilitate HIV self-management. The last comprehensive review of such mHealth...

Measures and metrics for feasibility of proof-of-concept studies with human immunodeficiency virus rapid point-of-care technologies: The evidence and the framework

2017

Objective: Pilot (feasibility) studies form a vast majority of diagnostic studies with point-of-care technologies but often lack use of clear measures/metrics and a consistent framework for reporting and evaluation. To...

A systematic review and narrative synthesis of interventions for parental human immunodeficiency virus disclosure

2017

INTRODUCTION: Disclosure of parental human immunodeficiency virus (HIV) infection to their children remains a difficult process for parents living with HIV (PLWH). In order to identify the best strategies to...

Health outcomes associated with crack-cocaine use: Systematic review and meta-analyses

2017

BACKGROUND: Crack-cocaine use is prevalent largely in socio-economically marginalized populations in the Americas. Its use has been associated with diverse health outcomes, yet no recent or systematic reviews of these...

Are religion and spirituality barriers or facilitators to treatment for HIV: A systematic review of the literature

2017

Much attention has been given to the relationship between religion/spirituality (R/S) and HIV in recent years, but comparatively little has been explored in regard to R/S and HIV testing, retention...

Zidovudine use in pregnancy and congenital malformations

2017

OBJECTIVE: There is inconsistent evidence that zidovudine use during pregnancy increases overall, cardiac, and male genital malformations. DESIGN: We conducted a systematic review and meta-analysis of zidovudine use and malformations...

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