SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV pre-exposure prophylaxis (PrEP): A review of current knowledge of oral systemic HIV PrEP in humans

2016

PURPOSE: Despite established HIV prevention strategies and broadly available diagnostic strategies in developed western countries, rates of HIV new infections remain high. Alternative strategies for HIV prevention, particularly among men...

A meta-analysis of the metabolic syndrome prevalence in the global HIV-infected population

2016

BACKGROUND: Cardio-metabolic risk factors are of increasing concern in HIV-infected individuals, particularly with the advent of antiretroviral therapy (ART) and the subsequent rise in longevity. However, the prevalence of cardio-metabolic...

Generic antiretroviral drugs and HIV care: An economic review

2016

The cost of HIV care in European countries is high. Direct medical costs, in France, have been estimated at 500,000Euros per patient’s lifetime (20,000 Euros/year/patient). Overall, 73% of these costs...

Critical review: Review of the efficacy, safety, and pharmacokinetics of raltegravir in pregnancy

2016

Raltegravir was previously considered an alternative antiretroviral in pregnancy because of limited data, but recent pregnancy guidelines recommend raltegravir as a preferred integrase treatment option. Data from published articles and...

Improving outpatient implementation of preexposure prophylaxis in men who have sex with men

2016

BACKGROUND AND PURPOSE: Preexposure prophylaxis (PrEP) has been shown to decrease the transmission of human immunodeficiency virus (HIV) when used in high-risk populations including men who have sex with men....

HIV prevalence in children and youth living on the street and subject to commercial sexual exploitation: A systematic review

2016

The aim of this review was to describe HIV prevalence in children and youth living on the street and subject to commercial sexual exploitation, and the studies’ characteristics in terms...

Determination the research priorities in the field of HIV/AIDS in Iran: A systematic review article

2016

BACKGROUND: HIV and AIDS have many different epidemiological, social and political aspects. The aim of this study was to determine the research priorities according to the necessary aspects of HIV...

Pros and cons of circumcision: An evidence-based overview

2016

Based on three large randomized controlled trials (RCTs) conducted in Africa, it can clearly be stated that circumcision lowers the risk of infection with the human immunodeficiency virus (HIV) and...

Fracture management in HIV positive individuals: A systematic review

2016

PURPOSE: Human immunodeficiency virus (HIV) infection could potentially play an important role in the management of fractures as they have been shown to affect fracture healing and the post-operative risk...

Housing stability and medication adherence among HIV-positive individuals in antiretroviral therapy: A meta-analysis of observational studies in the U.S.

2016

BACKGROUND: Previous research has produced inconsistent evidence of an association between housing stability and medication adherence among HIV-positive individuals in antiretroviral therapy. OBJECTIVE: We conducted a meta-analysis of the housing-adherence...

Disparities in the magnitude of human immunodeficiency virus-related opportunistic infections between high and low/middle-income countries: Is highly active antiretroviral therapy changing the trend?

2016

Opportunistic infections (OIs) cause significant morbidity/mortality in human immunodeficiency virus (HIV)-infected individuals globally. Disparities between high-income countries (HICs) and low/middle-income countries (LMICs) in the magnitude of HIV-related OIs in pre-highly...

Impact of ART on the fertility of HIV-positive women in sub-Saharan Africa

2016

OBJECTIVE: Understanding the fertility of HIV-positive women is critical to estimating HIV epidemic trends from surveillance data and to planning resource needs and coverage of prevention of mother-to-child transmission services...

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