SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Dermatological manifestation of HIV infection: Systematic review and meta-analysis

2025

Introduction Since its discovery in 1981, AIDS has become a significant global public health issue, impacting more than 38 million people worldwide with HIV. Despite a 32% reduction in new HIV...

Motivations, facilitators, and barriers of donation-based interventions in HIV and sexually transmitted infection research: A systematic review

2025

IMPORTANCE: Donation-based prosocial interventions involve someone receiving a free health service and then distributing or donating to support health services for others; examples within the HIV and sexually transmitted infection...

Psychosocial experience and coping of AIDS patients about the disease: A systematic review and qualitative meta-synthesis

2025

AIM: To systematically integrate the psychosocial experiences and coping mechanisms of AIDS patients after the disease, and to understand their true feelings, in order to provide a basis for better...

Moxibustion for human immunodeficiency virus and acquired immunodeficiency syndrome and its complications: A systematic review of randomized controlled trials

2025

OBJECTIVE: To comprehensively evaluate randomized controlled trials (RCTs) investigating the effects of moxibustion on people with human immunodeficiency virus (HIV) disease. METHODS: A systematic search was conducted across eight electronic...

Structural and socio-cultural barriers to HIV prevention tools among key populations: A scoping review

2025

INTRODUCTION: Despite decades of HIV prevention efforts, key populations – MSM, transgender people, PWUD, sex workers, and migrants – remain disproportionately affected by HIV. Although prevention tools are widely available,...

Effect of maternal HIV infection on birth outcomes among HIV positive women in Sub Saharan Africa: A systematic review and meta-analysis

2025

BACKGROUND: HIV is remaining the public health issues with an estimated of 39 million peoples are living with the virus till 2022. HIV positive pregnant women are at a greater...

A systematic review of mediation analysis frameworks in studies examining the determinants of cardiometabolic outcomes in people living with HIV

2025

Introduction Mediation analysis provides a more flexible mechanistic view of the causal relationship between HIV-related factors and cardiometabolic diseases. However, there is limited evidence on how mediation analysis is implemented...

Predictive value of neutrophil to lymphocyte ratio for the clinical outcomes of acquired immune deficiency syndrome: A systematic review and meta-analysis

2025

Objective: This study aimed to explore the predictive value of the neutrophil-to-lymphocyte ratio (NLR) for outcomes in Acquired Immune Deficiency Syndrome (AIDS) patients. Methods: PubMed, Embase, Cochrane, and Web of Science were...

Exercise interventions conducted among individuals with co-occurring HIV and unhealthy substance use: A systematic review

2025

Unhealthy substance use and physical inactivity are prevalent co-occurring risk factors for morbidity and mortality among people with HIV (PWH). Evidence-based exercise interventions targeting both risk factors are limited. We...

Cannabis use and HIV among Black sexually minoritized men: A systematic review and narrative analysis

2025

Objective: We conducted a systematic review evaluating the extant literature examining the impacts of cannabis use on HIV-related outcomes among Black sexual minoritized men (BSMM). Design: A systematic review. Methods: We conducted a...

Probability of vertical HIV transmission: A systematic review and meta-regression

2025

Background Eliminating HIV vertical transmission is a global priority and monitored by estimating paediatric HIV infections with the UNAIDS-supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART)...

Implementation of trauma-informed care into clinical HIV prevention and care settings: A decade of limited progress

2025

PURPOSE OF THE REVIEW: Trauma is common among people living with or at risk for HIV and associated with increased HIV risk and worse HIV care outcomes. Trauma-informed care (TIC)...

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