SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Comparative effectiveness of induction therapy for human immunodeficiency virus-associated cryptococcal meningitis: A network meta-analysis

2015

Background. Multiple international treatment guidelines recommend amphotericin-based combination regimens for induction therapy of cryptococcal meningitis. Yet, only 1 trial has reported a mortality benefit for combination amphotericin-flucytosine, and none have...

The syndemic illness of HIV and trauma: Implications for a trauma-informed model of care

2015

BACKGROUND: People living with HIV infection are disproportionately burdened by trauma and the resultant negative health consequences, making the combination of HIV infection and trauma a syndemic illness. Despite the...

A review of evidence-based care of symptomatic trichomoniasis and asymptomatic trichomonas vaginalis infections

2015

Trichomonas vaginalis is the most prevalent nonviral sexually transmitted infection, affecting an estimated 3.7 million women and men in the United States. Health disparities are prominent in the epidemiology of...

Predictors of internalised HIV-related stigma: A systematic review of studies in sub-Saharan Africa

2015

This systematic review aims to synthesise evidence on predictors of internalised HIV stigma amongst people living with HIV in sub-Saharan Africa. Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...

Advancing the sexual and reproductive health and human rights of women living with HIV: A review of UN, regional and national human rights norms and standards

2015

INTRODUCTION: The right to sexual and reproductive health (SRH) is an essential part of the right to health and is dependent upon substantive equality, including freedom from multiple and intersecting...

Leishmaniasis as a manifestation of immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients: A literature review

2015

INTRODUCTION: After the onset of highly active antiretroviral therapy (HAART), some HIV-infected patients present a severe inflammation in response to a latent or a previously treated opportunistic pathogen termed immune...

Retention in care prior to antiretroviral treatment eligibility in sub-Saharan Africa: A systematic review of the literature

2015

OBJECTIVE: We aimed at summarising rates and factors associated with retention in HIV care prior to antiretroviral treatment (ART) eligibility in sub-Saharan Africa. DESIGN: We conducted a systematic literature review...

HIV, antiretroviral therapy, and hypertensive disorders in pregnancy: A systematic review and meta-analysis

2015

BACKGROUND: There are data to suggest that infection with HIV or use of highly active antiretroviral therapy increases the risk of hypertensive disorders in pregnancy. This systematic review and meta-analysis...

Voluntary medical male circumcision for HIV prevention and early resumption of sexual activity: A literature review

2015

A number of programs have focused on scale-up and implementation research regarding voluntary medical male circumcision; however, there is limited research with regard to factors and strategies related to abstinence...

Systematic literature review and meta-analysis of renal function in human immunodeficiency virus (HIV)-infected patients treated with Atazanavir (ATV)-based regimens

2015

Some HIV antiretroviral therapies (ART) have been associated with renal toxicities, which become of increasing concern as HIV-infected patients age and develop comorbidities. The objective of this study was to...

Transitioning from adolescent to adult care in HIV

2015

Key take-home messages A range of social, psychological, economic, structural and cultural factors affect adolescents’ ability to transition from pediatric HIV care to adult care. Compared to HIV-negative adolescents, adolescents...

Interventions targeting sexual and reproductive health and rights outcomes of young people living with HIV: A comprehensive review of current interventions from sub-Saharan Africa

2015

BACKGROUND: A growing number of young people (ages 10-24) are living with HIV (YPLWH) in sub-Saharan Africa (SSA). These YPLWH have particular needs and challenges related to their sexual and...

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