SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Current trends and future directions in probiotics research for HIV/AIDS

2024

AIM: This study aims to comprehensively and systematically review the current status of research on probiotics and HIV/AIDS, while also exploring future research hotspots and trends in this domain. METHODS:...

Genetic variation on dolutegravir pharmacokinetics and relation to safety and efficacy outcomes: A systematic review

2024

BACKGROUND: Dolutegravir (DTG) is an antiviral agent used for the treatment of HIV, however, there is uncertainty over the influence of genetic variation on DTG exposure, and whether it has...

Effect of micronutrients on HIV-related clinical outcomes among adults living with HIV on antiretroviral therapy: Systematic review and meta-analysis

2024

Context: Micronutrient deficiencies are common and frequently co-occurring among people living with HIV (PLHIV) globally, with consequences for their health and clinical outcomes. Previous reviews of the influence of micronutrient supplementation...

Screening and prevention of HPV-related anogenital cancers in women living with HIV in Europe: Results from a systematic review

2024

Background Women living with HIV (WLWH) are at increased risk of human papillomavirus (HPV)-related cancers. Throughout Europe, there is great heterogeneity among guidelines for screening programmes, access to HPV testing...

Increased stigma, and physical and sexual violence against men who have sex with men and transgender women in sub-Saharan Africa: A qualitative evidence synthesis analyzing social and structural barriers to HIV testing and coping behaviors

2024

In sub-Saharan Africa, accessing HIV testing services is a significant challenge for men who have sex with men (MSM) and transgender women (TGW). In this qualitative evidence synthesis, our aim...

Understanding effective post-test linkage strategies for HIV prevention and care: A scoping review

2024

Introduction Following HIV testing services (HTS), the World Health Organization recommends prompt linkage to prevention and treatment. Scale‐up of effective linkage strategies is essential to achieving the global 95‐95‐95 goals...

Exploring optimal HAART adherence rates in Ethiopian adults: A systematic review and meta-analysis

2024

BACKGROUND: Optimal medication adherence is vital for the successful implementation of highly active antiretroviral therapy (HAART) in managing HIV infection. Global efforts aim to minimize the burden of antimicrobial resistance...

Mapping evidence on barriers to and facilitators of diagnosing noncommunicable diseases among people living with human immunodeficiency virus in low- and middle-income countries in Africa: A scoping review

2024

OBJECTIVES: To map the evidence on the barriers to and facilitators of diagnosing noncommunicable diseases among people living with HIV in low- and middle-income countries in Africa. INTRODUCTION: Noncommunicable diseases...

Variation of adverse drug events in different settings in Africa: A systematic review

2024

BACKGROUND: Adverse drug events (ADEs) represent challenges affecting Africa’s healthcare systems owing to the increased healthcare expenditure and negative health outcomes of ADEs. OBJECTIVES: We aimed to systematically review published...

Association between HIV and acquisition of rifamycin resistance with first-line TB treatment: A systematic review and meta-analysis

2024

BACKGROUND: Multi-drug or rifamycin-resistant tuberculosis (MDR/RR-TB) is an important public health concern, including in settings with high HIV prevalence. TB drug resistance can be directly transmitted or arise through resistance...

Prevalence of extrapulmonary tuberculosis among people living with HIV/AIDS in Southeast Asia: A systematic review and meta-analysis

2024

The dual burden of human immunodeficiency virus (HIV) and tuberculosis (TB) impacts people living with HIV (PLHIV) coinfected with TB. Although some primary studies have been reported on the burden...

A systematic review and meta-analysis evaluating the effectiveness of minimally supervised home and community exercise interventions in improving physical activity, body adiposity and quality of life in adults living with HIV

2024

People living with HIV (PLWH) are physically inactive and risk cardiometabolic dysfunction. Home and community exercise (HCE) is pragmatic, cost-effective and improves health in varied chronic conditions. This review aimed...

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