SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Nutrition assessment, counseling, and support interventions to improve health-related outcomes in people living with HIV/AIDS: A systematic review of the literature

2015

BACKGROUND: Although numerous studies have shown that severe to moderate wasting at the time of antiretroviral therapy initiation is strongly predictive of mortality, it remains unclear whether nutritional interventions at...

Elevated homocysteine levels in human immunodeficiency virus-infected patients under antiretroviral therapy: A meta-analysis

2015

AIM: To evaluate the association between the levels of homocysteine (Hcy), folate, vitamin B12 in human immunodeficiency virus (HIV)-infected patients who were treated with antiretroviral therapy (ART) or not treated...

Pregnancy and HIV disease progression: A systematic review and meta-analysis

2015

OBJECTIVE: To assess whether pregnancy accelerates HIV disease progression. METHODS: Studies comparing progression to HIV-related illness, low CD4 count, AIDS-defining illness, HIV-related death, or any death in HIV-infected pregnant and...

Physical impairment in HIV infections and AIDS: Responses to resistance and aerobic training

2014

AIM: The aim of this paper was to examine impairments in muscle strength and aerobic power associated with HIV and AIDS, to define optimal regimes of resistance and aerobic training,...

Is there enough evidence to use bisphosphonates in HIV-infected patients? A systematic review and meta-analysis

2014

An increased prevalence of osteopenia and osteoporosis has been observed in HIV-infected cohorts. We investigated the effect of bisphosphonates on bone mineral density in adults with HIV infection. Outcomes of...

Systematic review of facility-based sexual and reproductive health services for female sex workers in Africa

2014

BACKGROUND: Several biological, behavioural, and structural risk factors place female sex workers (FSWs) at heightened risk of HIV, sexually transmitted infections (STIs), and other adverse sexual and reproductive health (SRH)...

Evidence informing the intersection of HIV, aging and health: A scoping review

2014

The growing number of people over age 50 with HIV requires research, policy, and practice to develop a more comprehensive understanding of the health consequences of HIV in older individuals....

Cardiovascular manifestations of HIV infection in children

2014

BACKGROUND: HIV infection in children is now considered as a chronic condition, in which various non-infectious complications may occur, including those affecting the developing cardiovascular system. As children are expected...

The validity of the modification of diet in renal disease formula in HIV-infected patients: A systematic review

2014

RATIONALE, AIMS AND OBJECTIVES: Renal dysfunction is highly prevalent in HIV-infected patients and may require dose adjustment of renally excreted antiretroviral drugs. The Modification of Diet in Renal Disease (MDRD)-4...

Effect of home-based interventions on virologic outcomes in adults receiving antiretroviral therapy in Africa: a meta-analysis

2014

BACKGROUND: The success of adherence to combination antiretroviral therapy (ART) in sub-Saharan Africa is hampered by factors that are unique to this setting. Home based interventions have been identified as...

Alcohol and sexual risk reduction interventions among people living in Russia: A systematic review and meta-analysis

2014

Russia has one of the highest rates of alcohol consumption and is experiencing one of the fastest-growing HIV epidemics in the world. Given these co-occurring health problems, we systematically reviewed...

Review: An urgent need for research on factors impacting adherence to and retention in care among HIV-positive youth and adolescents from key populations

2014

INTRODUCTION: The 50% increase in HIV-related deaths in youth and adolescents (aged 10-24) from 2005 to 2012 highlights the need to improve HIV treatment and care in this population, including...

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