SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Etravirine as a switching option for patients with HIV RNA suppression: A review of recent trials

2014

Unlike other nonnucleoside reverse transcriptase inhibitors, etravirine is only approved for use in treatment-experienced patients. In the DUET 1 and 2 trials, 1203 highly treatment-experienced patients were randomized to etravirine...

Yellow fever vaccine for patients with HIV infection

2014

BACKGROUND: Yellow fever (YF) is an acute viral haemorrhagic disease prevalent in tropical Africa and Latin America. The World Health Organization (WHO) estimates that there are 200,000 cases of YF...

Hormonal contraceptive methods and risk of HIV acquisition in women: A systematic review of epidemiological evidence

2014

Whether use of various types of hormonal contraception (HC) affect risk of HIV acquisition is a critical question for women’s health. For this systematic review, we identified 22 studies published...

Retention in care and adherence to ART are critical elements of HIV care interventions

2014

Retention in care and adherence to antiretroviral treatment (ART) are critical elements of HIV care interventions and are closely associated with optimal individual and public health outcomes and cost effectiveness....

Emerging trends of HIV drug resistance in Chinese HIV-infected patients receiving first-line highly active antiretroviral therapy: A systematic review and meta-analysis

2014

BACKGROUND: Highly active antiretroviral therapy (HAART) has led to a dramatic decrease in AIDS-related morbidity and mortality through sustained suppression of human immunodeficiency virus (HIV) replication and reconstitution of the...

Antiretroviral therapy uptake, attrition, adherence and outcomes among HIV-infected female sex workers: A systematic review and meta-analysis.

2014

PURPOSE: We aimed to characterize the antiretroviral therapy (ART) cascade among female sex workers (FSWs) globally. METHODS: We systematically searched PubMed, Embase and MEDLINE in March 2014 to identify studies...

Motivational interviewing

2014

Key tale-home messages Interventions that make use of motivational interviewing can be effective in changing risk behaviours for people living with HIV; the longer the motivational interviewing intervention, the more...

Heterosexual risk of HIV transmission per sexual act under combined antiretroviral therapy: Systematic review and bayesian modeling

2014

BACKGROUND: Although essential for patient counseling and quality of life of human immunodeficiency virus (HIV)-infected individuals, the risk of HIV transmission during 1 unprotected sex act with an HIV-infected person...

Diagnosing acute and prevalent HIV-1 infection in young African adults seeking care for fever: A systematic review and audit of current practice

2014

Fever is a common complaint in HIV-1 infected adults and may be a presenting sign of acute HIV-1 infection (AHI). We investigated the extent to which HIV-1 infection was considered...

Estimating per-act HIV transmission risk: A systematic review

2014

BACKGROUND: Effective HIV prevention programs rely on accurate estimates of the per-act risk of HIV acquisition from sexual and parenteral exposures. We updated the previous risk estimates of HIV acquisition...

Is there scope for cost savings and efficiency gains in HIV services? A systematic review of the evidence from low- and middle-income countries

2014

OBJECTIVE: To synthesize the data available–on costs, efficiency and economies of scale and scope–for the six basic programmes of the UNAIDS Strategic Investment Framework, to inform those planning the scale-up...

Community-acquired bacterial bloodstream infections in HIV-infected patients: A systematic review

2014

Information on community-acquired bacterial bloodstream infections (BSIs) in individuals infected with human immunodeficiency virus (HIV) is limited. We conducted a systematic literature review. The case fraction of community-acquired bacterial BSIs...

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