SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Barriers to hepatitis C antiviral therapy in HIV/HCV co-infected patients in the United States: A review

2014

This review synthesized the literature for barriers to HCV antiviral treatment in persons with HIV/HCV co-infection. Searches of PubMed, Embase, CINAHL, and Web of Science were conducted to identify relevant...

Predictors and correlates of adherence to combination antiretroviral therapy (ART) for chronic HIV infection: A meta-analysis

2014

BACKGROUND: Adherence to combination antiretroviral therapy (ART) is a key predictor of the success of human immunodeficiency virus (HIV) treatment, and is potentially amenable to intervention. Insight into predictors or...

Substance abuse treatment in persons with HIV/AIDS: Challenges in managing triple diagnosis

2014

Clinical management of HIV must account for the “triple diagnosis” of HIV, psychiatric diagnosis, and substance use disorders and requires integrated treatment services that focus beyond just mitigation of substance...

Systemic preexposure prophylaxis for HIV: Translating clinical data to clinical practice

2014

OBJECTIVE: To assess the real-world implications of oral tenofovir-emtricitabine (TDF-FTC) for HIV preexposure prophylaxis (PrEP) in clinical practice and highlight important considerations for its implementation. DATA SOURCES: A search of...

Impact of point-of-care CD4 testing on linkage to HIV care: A systematic review

2014

INTRODUCTION: Point-of-care testing for CD4 cell count is considered a promising way of reducing the time to eligibility assessment for antiretroviral therapy (ART) and of increasing retention in care prior...

HIV among people who inject drugs in the Middle East and North Africa: Systematic review and data synthesis.

2014

BACKGROUND: It is perceived that little is known about the epidemiology of HIV infection among people who inject drugs (PWID) in the Middle East and North Africa (MENA). The primary...

Understanding structural barriers to accessing HIV testing and prevention services among black men who have sex with men (BMSM) in the United States

2014

Structural-level factors have contributed to the substantial disproportionate rates of HIV among Black men who have sex with men (BMSM) in the United States. Despite insufficient HIV testing patterns, however,...

Basis of selection of first and second line highly active antiretroviral therapy for HIV/AIDS on genetic barrier to resistance: A literature review

2014

Long-term management of HIV/AIDS is at risk of increasing drug resistance1. Booster protease inhibitor (PI) and thymidine analogue-containing regimens have a high genetic barrier to resistance. Non-thymidine-analogue triple nucleoside/nucleotide reverse...

Scarcity of protective items against HIV and other bloodborne infections in 13 low- and middle-income countries

2014

OBJECTIVE: To assess protection of surgical healthcare workers against HIV and other bloodborne infections in low- and middle-income countries (LMICs). METHODS: Literature review based on recent studies assessing baseline surgical...

Brief sexuality communication-a behavioural intervention to advance sexually transmitted infection/HIV prevention: A systematic review

2014

BACKGROUND: Throughout the last decade substantial research has been undertaken to develop evidence-based behaviour change interventions for sexual health promotion. Primary care could provide an opportunistic entry for brief sexual...

Cobicistat: A new opportunity in the treatment of HIV disease?

2014

INTRODUCTION: Cobicistat (Cobi), a selective novel CYP3A4 inhibitor, is an orally administered, non-antiretroviral pharmacokinetic enhancer which boosts the plasma levels of several drugs, including HIV-1 protease inhibitors and the integrase...

Depression and adherence to antiretroviral therapy in low-, middle- and high-income countries: A systematic review and meta-analysis

2014

We investigated the associations between depressive symptoms and adherence to antiretroviral therapy (ART) among people living with HIV (PLHIV). We searched the PubMed, EMBASE and Cochrane CENTRAL databases for studies...

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