SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Text message intervention designs to promote adherence to antiretroviral therapy (ART): A meta-analysis of randomized controlled trials

2014

BACKGROUND: The efficacy of antiretroviral therapy depends on patient adherence to a daily medication regimen, yet many patients fail to adhere at high enough rates to maintain health and reduce...

Risk of melanoma in people with HIV/AIDS in the pre- and post-HAART eras: A systematic review and meta-analysis of cohort studies

2014

OBJECTIVE: Following the introduction of highly active antiretroviral therapy (HAART) the risk of AIDS-defining cancers decreased but incidence of many non-AIDS-defining cancers has reportedly increased in those with HIV/AIDS. Whether...

Human immunodeficiency virus and nodular regenerative hyperplasia of liver: A systematic review

2014

AIM: To investigate the diagnosis, pathogenesis, natural history, and management of nodular regenerative hyperplasia (NRH) in patients with human immunodeficiency virus (HIV). METHODS: We performed a systematic review of the...

Gay men’s attitudes towards and perceptions of viral load and treatment as prevention

2014

Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...

Metabolic alterations in HIV-infected pregnant women: Moving to metabolic tailoring of antiretroviral drugs

2014

The most striking effect of increased survival and improved quality of life in HIV-infected women undergoing antiretroviral therapy is the feasibility of motherhood-desire satisfaction. However, such advantages are often associated...

Systematic review of the performance of HIV viral load technologies on plasma samples

2014

BACKGROUND: Viral load (VL) monitoring is the standard of care in developing country settings for detecting HIV treatment failure. Since 2010 the World Health Organization has recommended a phase-in approach...

Does this adult patient have early HIV infection?: The Rational Clinical Examination systematic review

2014

IMPORTANCE: Timely identification of human immunodeficiency virus (HIV) infection in adults can contribute to reduced mortality and likelihood of further HIV transmission. During the first 6 months after infection, known...

Factors affecting adherence to short-course ARV prophylaxis for preventing mother-to-child transmission of HIV in sub-Saharan Africa: A review and lessons for future elimination

2014

Despite the biomedical potential to eliminate vertical HIV transmission, drug adherence to short regimens is often sub-optimal. To inform future programmes, we reviewed evidence on the factors influencing maternal and...

Vertical transmission of hepatitis C: Systematic review and meta-analysis

2014

BACKGROUND: We conducted a systematic review of estimates of hepatitis C virus (HCV) vertical transmission risk to update current estimates published over a decade ago. METHODS: PubMed and Embase were...

Association between HIV/AIDS and multi-drug resistance tuberculosis: A systematic review and meta-analysis

2014

BACKGROUND: Human immunodeficiency virus (HIV), multi-drug resistant tuberculosis (MDR) is emerging as major challenge facing tuberculosis control programs worldwide particularly in Asia and Africa. Findings from different studies on associations...

Systematic review and meta-analysis of HIV prevalence among men in militaries in low income and middle income countries

2014

OBJECTIVES: To determine whether the current HIV prevalence in militaries of low-income and middle-income countries is higher, the same, or lower than the HIV prevalence in the adult male population...

Contraceptive methods and risk of HIV acquisition or female-to-male transmission

2014

Effective family planning with modern contraception is an important intervention to prevent unintended pregnancies which also provides personal, familial, and societal benefits. Contraception is also the most cost-effective strategy to...

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