SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Herpes simplex virus type 2 and HIV disease progression: A systematic review of observational studies

2013

BACKGROUND: Herpes simplex virus type 2 (HSV-2) is a common co-infection among HIV-infected adults that is hypothesized to accelerate HIV disease progression. METHODS: We searched Medline, EMBASE, relevant conference proceedings...

A systematic review of the screening accuracy of the HIV Dementia Scale and International HIV Dementia Scale

2013

BACKGROUND: The HIV Dementia Scale (HDS) and International HIV Dementia Scale (IHDS) are brief tools that have been developed to screen for and aid diagnosis of HIV-associated dementia (HAD). They...

Male involvement in prevention programs of mother to child transmission of HIV: A systematic review to identify barriers and facilitators

2013

BACKGROUND: Many reports point to the beneficial effect of male partner involvement in programs for the prevention of mother-to-child-transmission (PMTCT) of HIV in curbing pediatric HIV infections. This paper summarizes...

Impact of antiretroviral drugs in pregnant women and their children in Africa: HIV resistance and treatment outcomes

2013

The global community has committed itself to eliminating new pediatric HIV infections by 2015 and improving maternal, newborn, and child health and survival in the context of HIV. Such objectives...

Systematic review and meta-analysis: Influence of smoking cessation on incidence of pneumonia in HIV

2013

BACKGROUND: Smoking is common in people infected with HIV but cessation support is not a routine part of clinical care. The aim was to assess whether smoking is a risk...

Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers

2013

Background: Extensive evidence shows that well over 50% of people prefer to be cared for and to die at home provided circumstances allow choice. Despite best efforts and policies, one-third...

A systematic review of behavioral interventions to prevent HIV infection and transmission among heterosexual, adult men in low-and middle-income countries

2013

Prevention of new HIV infections needs to move to the forefront in the fight against HIV and AIDS. In the current economic crisis, low- and middle-income countries (LMICs) should invest...

The effectiveness and cost implications of task-shifting in the delivery of antiretroviral therapy to HIV-infected patients: A systematic review

2013

INTRODUCTION: Human resource shortages are a challenge to the rollout of antiretroviral therapy (ART) for HIV-infected patients, particularly in sub-Saharan Africa. Task-shifting has been recommended as an approach to reduce...

Modeling the cost-effectiveness of HIV treatment: how to buy the most ‘health’ when resources are limited

2013

PURPOSE OF REVIEW: To summarize recent cost-effectiveness analyses (CEAs) that evaluate optimal treatment strategies for persons living with HIV/AIDS (PLWHA). RECENT FINDINGS: Efforts to attain universal coverage of current treatment...

HIV and the risk of direct obstetric complications: A systematic review and meta-analysis

2013

BACKGROUND: Women of reproductive age in parts of sub-Saharan Africa are faced both with high levels of HIV and the threat of dying from the direct complications of pregnancy. Clinicians...

Systematic review of HIV transmission between heterosexual serodiscordant couples where the HIV-positive partner is fully suppressed on antiretroviral therapy

2013

BACKGROUND: The risk of sexual HIV transmission in serodiscordant couples when the HIV-positive partner has full virologic suppression on combination antiretroviral therapy (cART) is debated. This study aims to systematically...

Aging, antiretrovirals, and adherence: A meta analysis of adherence among older HIV-infected individuals

2013

INTRODUCTION: Older adults are generally considered to be at greater risk for medication non-adherence due to factors such as medication complexity, side effects, cost, and cognitive decline. However, this generalization...

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