SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The cost-effectiveness of syphilis screening in pregnant women: A systematic literature review

2024

INTRODUCTION: The cost-effectiveness study of syphilis screening in pregnant women has not been synthesized. This study aimed to synthesize the economic evidence on the cost-effectiveness of syphilis screening in pregnant...

Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: A systematic review and meta-analysis

2024

Background The World Health Organization (WHO) recommends tenofovir disoproxil fumarate (TDF)-based oral pre-exposure prophylaxis (PrEP), the dapivirine vaginal ring, and long-acting intramuscular injectable cabotegravir (CAB-LA) for HIV prevention in populations...

Interventions aimed at increasing syphilis screening among non-pregnant individuals in healthcare settings: A systematic review and meta-analysis

2024

Syphilis remains a pressing public health concern with potential severe morbidity if left untreated. To improve syphilis screening, targeted interventions are crucial, especially in at-risk populations. This systematic review synthesises...

Population percentage and population size of men who have sex with men in the United States, 2017–2021: Meta-analysis of 5 population-based surveys

2024

BACKGROUND: Male-to-male sexual transmission continues to account for the greatest proportion of new HIV diagnoses in the United States. However, calculating population-specific surveillance metrics for HIV and other sexually transmitted...

The prevalence and moderating factors of sleep disturbances in people living with HIV: A systematic review and meta-analysis

2024

This systematic review and meta-analysis aimed to investigate the prevalence of self-reported sleep disturbances in people living with HIV considering the effects of age, depression, anxiety, CD4 cell counts, time...

Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation

2024

HIV/AIDS remains one of the world’s most significant public health and economic challenges, with approximately 36 million people currently living with the disease. Considerable progress has been made to reduce...

Innovation and implementation determinants of HIV testing and linkage-to-care in the U.S.: A systematic review

2024

OBJECTIVE: To identify innovation and implementation determinants of HIV testing, diagnosis, and linkage-to-care in the U.S. DATA SOURCES AND STUDY SETTING: Between November 2020 and January 2022, a broad search...

A critical review of mpox outbreaks, risk factors, and prevention efforts in Africa: Lessons learned and evolving practices

2024

OBJECTIVES: In recent years, mpox, a zoonotic disease caused by the mpox virus, has transcended its primary association with Central and West Africa, emerging as a global public health concern....

Challenges of the postpartum period in women living with HIV

2024

Key take-home messages

HIV-1 antiretroviral drug resistance in Mozambique: A systematic review and meta-analysis

2024

This systematic review assessed the prevalence of transmitted and acquired HIV drug resistance (HIVDR) and the associated risk factors in Mozambique. A search of the PubMed, Cochrane, B-On, and Scopus...

Burden of mortality and its predictors among TB-HIV co-infected patients in Ethiopia: Systematic review and meta-analysis

2024

BACKGROUND: Human immunodeficiency virus (HIV) and tuberculosis (TB) are still the two major deadly pandemics globally, causes 167,000 deaths in 2022. The two lethal combinations pose a substantial challenge to...

Preexposure prophylaxis and intimate partner violence among gay, bisexual, and other men who have sex with men: A global scoping review of the literature

2024

Men who have sex with men (MSM) experience intimate partner violence (IPV) and are at an elevated risk of HIV acquisition. Preexposure prophylaxis (PrEP) is an effective preventative measure against...

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