SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Antiretroviral therapy for prevention of tuberculosis in adults with HIV: A systematic review and meta-analysis

2012

BACKGROUND: Human immunodeficiency virus (HIV) infection is the strongest risk factor for developing tuberculosis and has fuelled its resurgence, especially in sub-Saharan Africa. In 2010, there were an estimated 1.1...

The effects of dietary intervention on HIV dyslipidaemia: A systematic review and meta-analysis

2012

Background: Efficacy of dietary intervention for treatment and prevention of HIV-related lipid disturbances has not been well established. Methods: We conducted a systematic search of electronic databases supplemented with manual...

Stress and coping in women living with HIV: A meta-analytic review

2012

To examine effects between stressors and coping mechanisms on behavioral health outcomes a meta-analysis was conducted using forty empirical articles which sampled 7,602 adult women living with HIV/AIDS in the...

Gay and bisexual men rural outreach

2012

Key take-home messages The internet has been to be an effective tool to reach populations that are geographically and/or socially isolated. Rural men who sex with men (MSM) typically have...

Is there an increased risk of post-operative surgical site infection after orthopaedic surgery in HIV patients? A systematic review and meta-analysis

2012

Background: There is dilemma as to whether patients infected with the Human Immunodeficiency Virus (HIV) requiring implant orthopaedic surgery are at an increased risk for post-operative surgical site infection (SSI)....

Understanding the role of family on sexual-risk decisions of young women: A systematic review

2012

Girls and young women are at high risk of infection with human immunodeficiency virus (HIV). Many research studies suggest that the family plays an important role in young women’s sexual-risk...

Meta-analysis of the safety, tolerability, and efficacy of lopinavir/ritonavir-containing antiretroviral therapy in HIV-1-infected women

2012

PURPOSE: Women comprise ≯50% of HIV-infected patients, yet safety, tolerability, and efficacy data in women taking antiretrovirals (ARVs) are limited. Lopinavir/ ritonavir (LPV/r)-anchored regimens are globally the most widely prescribed...

Screening for HIV: Systematic review to update the 2005 U.S. Preventive Services Task Force recommendation

2012

BACKGROUND: A 2005 U.S. Preventive Services Task Force (USPSTF) review found good evidence that HIV screening is accurate and that antiretroviral therapy (ART) for immunologically advanced disease is associated with...

Very late initiation of HAART impairs treatment response at 48 and 96 weeks: Results from a meta-analysis of randomized clinical trials

2012

BACKGROUND: Initiation of highly active antiretroviral therapy (HAART) with low CD4 lymphocyte counts is associated with AIDS-related and non-AIDS-related events and increased mortality. However, no clear association has been found...

Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: A challenge to success

2012

Objective: There is considerable research around the morbidity and mortality related to noncommunicable diseases (NCDs), particularly cardiovascular disease and diabetes, among people living with HIV/AIDS (PLWHA) in resource-richer settings. Less...

Effects of vitamin D deficiency and combination antiretroviral therapy on bone in HIV-positive patients

2012

Objectives: In the era of combination antiretroviral therapy (cART), vitamin D deficiency, low bone mineral density (BMD) and fractures have emerged as subjects of concern in HIV-positive patients. Testing for...

Head-to-head comparison of accuracy of a rapid point-of-care HIV test with oral versus whole-blood specimens: A systematic review and meta-analysis

2012

BACKGROUND: The focus on prevention strategies aimed at curbing the HIV epidemic is growing, and therefore screening for HIV has again taken centre stage. Our aim was to establish whether...

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