SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Invasive non-typhoidal salmonella disease: An emerging and neglected tropical disease in Africa

2012

Invasive strains of non-typhoidal salmonellae have emerged as a prominent cause of bloodstream infection in African adults and children, with an associated case fatality of 20-25%. The clinical presentation of...

An updated systematic review and meta-analysis on the treatment of active tuberculosis in patients with HIV infection

2012

Background. Human immunodeficiency virus (HIV) infection increases the risk of poor outcomes in active tuberculosis. We updated a systematic review and meta-analysis assessing the effects of duration of rifamycins, schedule...

The safety of yellow fever vaccine 17D or 17DD in children, pregnant women, HIV+ individuals, and older persons: Systematic review

2012

Yellow fever vaccine provides long-lasting immunity. Rare serious adverse events after vaccination include neurologic or viscerotropic syndromes or anaphylaxis. We conducted a systematic review of adverse events associated with yellow...

Mannose-binding lectin and the risk of HIV transmission and disease progression in children: A systematic review

2012

BACKGROUND: Mannose-binding lectin (MBL) can activate the complement system by binding to carbohydrates, such as those presented on the HIV virion surface. It is unclear whether genetically determined MBL deficiency...

Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: A systematic review and meta-analysis

2012

BACKGROUND: 100 million people worldwide are homeless; rates of mortality and morbidity are high in this population. The contribution of infectious diseases to these adverse outcomes is uncertain. Accurate estimates...

Determinants of male involvement in maternal and child health services in sub-Saharan Africa: A review

2012

INTRODUCTION: Male participation is a crucial component in the optimization of Maternal and Child Health (MCH) services. This is especially so where prevention strategies to decrease Mother-to-Child Transmission (MTCT) of...

The impact of education on sexual behavior in sub-Saharan Africa: A review of the evidence

2012

Many studies have attempted to determine the relationship between education and HIV status. However, a complete and causal understanding of this relationship requires analysis of its mediating pathways, focusing on...

No association of abacavir use with myocardial infarction: Findings of an FDA meta-analysis

2012

BACKGROUND: Several studies have reported an association between abacavir (ABC) exposure and increased risk of myocardial infarction (MI) among HIV-infected individuals. Randomized controlled trials (RCTs) and a pooled analysis by...

Mindfulness-based therapy for people living with HIV

2012

Key take-home messages Findings from five systematic reviews evaluating mindfulness-based interventions (MBIs) — specifically mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) — have found beneficial effects on mental...

HIV-associated oral lesions as an indicator for HAART failure: A review

2012

INTRODUCTION: HIV-associated oral lesions have been used as clinical indicators of HIV infection and/or HIV-disease progression. It is well established that there is a significant reduction in the incidence of...

HIV prevention interventions to reduce racial disparities in the United States: A systematic review

2012

Racial and ethnic minorities are disproportionately affected by HIV/AIDS in the United States despite advances in prevention methodologies. The goal of this study was to systematically review the past 30...

Integrating prevention of mother-to-child HIV transmission programs to improve uptake: A systematic review

2012

Background: We performed a systematic review to assess the effect of integrated perinatal prevention of mother-to-child transmission of HIV interventions compared to non- or partially integrated services on the uptake...

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