SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV in the Middle East and North Africa: Priority, culture, and control

2013

OBJECTIVES: This study aimed to assess the priority of HIV/AIDS in the Middle East and North Africa region and compare it with other regions. This review examines the social, cultural...

HIV incidence in Asia: A review of available data and assessment of the epidemic

2013

Rates of new HIV infections in Asia are poorly characterized, likely resulting in knowledge gaps about infection trends and the most important areas to target for interventions. We conducted a...

Impact of baseline HIV-1 RNA levels on initial highly active antiretroviral therapy outcome: A meta-analysis of 12,370 patients in 21 clinical trials

2013

BACKGROUND: Individual randomized trials of first-line antiretroviral treatment do not consistently show an association between higher baseline HIV-1 RNA and lower efficacy. METHODS: A MEDLINE search identified 21 HIV clinical...

Systematic review and meta-analysis: Influence of smoking cessation on incidence of pneumonia in HIV

2013

BACKGROUND: Smoking is common in people infected with HIV but cessation support is not a routine part of clinical care. The aim was to assess whether smoking is a risk...

Nevirapine-based regimens in HIV-infected antiretroviral-naive patients: Systematic review and meta-analysis of randomized controlled trials.

2013

BACKGROUND: Nevirapine belongs to the group of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and is commonly administered in first-line treatment of HIV infection. OBJECTIVE: Systematic review and meta-analysis was undertaken to...

HIV testing and counselling for migrant populations living in high-income countries: A systematic review

2013

BACKGROUND: The barriers to HIV testing and counselling that migrants encounter can jeopardize proactive HIV testing that relies on the fact that HIV testing must be linked to care. We...

Causal inference regarding infectious aetiology of chronic conditions: A systematic review

2013

Background: Current guidelines recommend screening all people living with human immunodeficiency virus (PLHIV) who have a CD4 count ≤100 cells/µL for cryptococcal antigen (CrAg) to identify those patients who could benefit...

Primary prophylaxis for cryptococcal meningitis and impact on mortality in HIV: A systematic review and meta-analysis

2013

Aim: To determine the role of primary antifungal prophylaxis in the prevention of cryptococcal meningitis and all-cause mortality in advanced HIV infection. Materials & methods: This was a systematic review...

Intersectionality in HIV and other health-related research

2013

Key take-home messages Human experiences cannot be reduced to singular characteristics as these characteristics interact with others to produce health outcomes. Using social categories, such as class, race, gender, sexual...

A systematic review to quantitatively evaluate ‘Stepping Stones’: A participatory community-based HIV/AIDS prevention intervention

2013

This first independent systematic review examined evidence for the effectiveness of the stepping stones intervention in HIV prevention. To reduce HIV transmission it addresses gender roles and promotes equitable relationships....

Towards universal voluntary HIV testing and counselling: A systematic review and meta-analysis of community-based approaches

2013

BACKGROUND: Effective national and global HIV responses require a significant expansion of HIV testing and counselling (HTC) to expand access to prevention and care. Facility-based HTC, while essential, is unlikely...

Systematic review of antiretroviral-associated lipodystrophy: Lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction

2013

BACKGROUND: Lipoatrophy and/or central fat gain are observed frequently in patients on antiretroviral therapy (ART). Both are assumed to be antiretroviral adverse drug reactions. METHODS: We conducted a systematic review...

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