SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Sex differences in adherence to highly active antiretroviral therapy: A meta-analysis

2012

Observational studies have found that women tend to have lower adherence to highly active antiretroviral therapy (HAART) than men do, though no meta-analysis has yet investigated this trend. The aims...

Effect of CCR5-32 heterozygosity on HIV-1 susceptibility: A meta-analysis

2012

So far, many studies have investigated the distribution of CCR5 genotype between HIV-1 infected patients and uninfected people. However, no definite results have been put forward about whether heterozygosity for...

A systematic review of education for the prevention of HIV/AIDS among older adults

2012

Through a comprehensive literature search, the authors of this systematic review identified 21 articles focused on primary prevention of HIV/AIDS for adults aged 50 and over. Three major challenges to...

Factors that affect HIV testing and counseling services among heterosexuals in Canada and the United Kingdom: An integrated review

2012

OBJECTIVE: To examine factors that affect the utilization of HIV testing and counseling (HTC) services among heterosexual populations in Canada and the U.K. METHODS: We conducted an integrated review of...

Acute coronary syndromes in human immunodeficiency virus patients: A meta-analysis investigating adverse event rates and the role of antiretroviral therapy

2012

AIMS: Highly active antiretroviral therapy (HAART) dramatically reduces human immunodeficiency virus (HIV)-associated morbidity and mortality, but adverse effects of HAART are becoming an increasing challenge, especially in the setting of...

A role for depression in sexual risk reduction for women? A meta-analysis of HIV prevention trials with depression outcomes

2012

Rates of HIV/AIDS and depression in women are significant public health concerns. The current meta-analysis tested the hypothesis that depression levels moderate change in sexual risk behavior in women participating...

Exploring the concept of HIV-related stigma

2012

BACKGROUND. HIV infection is a chronic, manageable illness. Despite advances in the care and treatment of people living with HIV infection, HIV-related stigma remains a challenge to HIV testing, care,...

Isoniazid preventive therapy in correctional facilities: A systematic review

2012

Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide and the main cause of death in correctional facilities in middle- and low-income countries. Due to the closed environment...

Micronutrient supplementation in pregnant women with HIV infection

2012

Micronutrient deficiencies are widespread and compound the effects of HIV disease; micronutrient supplements may be effective and safe in reducing this burden. To assess whether micronutrient supplements are effective and...

Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission

2012

OBJECTIVE: The potential for changing HIV-1 virulence has significant implications for the AIDS epidemic, including changing HIV transmission rates, rapidity of disease progression, and timing of ART. Published data to...

Placebo response changes depending on the neuropathic pain syndrome: Results of a systematic review and meta-analysis

2012

Objective. To compare placebo responses in neuropathic pain syndromes. Design. Systematic literature review and meta-analysis. Setting and Patients. Randomized placebo-controlled trials assessing pain intensity or pain relief in any neuropathic...

Effect of cotrimoxazole on mortality in HIV-infected adults on antiretroviral therapy: A systematic review and meta-analysis

2012

OBJECTIVE: To determine whether cotrimoxazole reduces mortality in adults receiving antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection in low- and middle-income countries through a systematic review and meta-analysis....

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