SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Comparative effectiveness of efavirenz-based antiretroviral regimens in resource-limited settings

2012

Efavirenz (EFV) is a non-nucleoside widely used as first-line therapy for HIV-1 infection. Most of the research available on EFV comes from trials performed in industrialized countries and only a...

Racial/ethnic disparities in HIV infection among people who inject drugs: An international systematic review and meta-analysis

2012

AIMS: The Ethnic Minority Meta-Analysis (EMMA) aims to assess racial/ethnic disparities in HIV infection among people who inject drugs (PWID) across various countries. This is the first report of the...

Prevention of HIV among older adults: A literature review and recommendations for future research

2012

OBJECTIVE: This study reviews the existing literature on the prevention of HIV among older adults, including universal and indicated prevention programs and prevention strategies. METHOD: A literature search was conducted...

Social and structural factors associated with HIV disease progression among illicit drug users: A systematic review

2012

OBJECTIVE: To systematically review factors associated with HIV disease progression among illicit drug users, focusing on exposures exogenous to individuals that likely shape access and adherence to HIV treatment. DESIGN:...

The effectiveness of interventions using electronic reminders to improve adherence to chronic medication: A systematic review of the literature

2012

BACKGROUND: Many patients experience difficulties in adhering to long-term treatment. Although patients’ reasons for not being adherent are diverse, one of the most commonly reported barriers is forgetfulness. Reminding patients...

Pathologising healthy children? A review of the literature exploring the mental health of HIV-affected children in sub-Saharan Africa

2012

This article reviews the expanding body of literature that examines the mental health of HIV-affected children in sub-Saharan Africa. Focusing on primary research across disciplines and methodologies, the review examines...

A systematic review of antiretroviral adherence interventions for HIV-infected people who use drugs

2012

HIV-infected persons who use drugs (PWUDs) are particularly vulnerable for suboptimal combination antiretroviral therapy (cART) adherence. A systematic review of interventions to improve cART adherence and virologic outcomes among HIV-infected...

Mother’s CD4+ count moderates the risk associated with higher parity for late postnatal HIV-free survival of breastfed children: An individual patient data meta-analysis of randomized controlled trials

2012

Risk association studies of late postnatal outcomes for children breastfed by HIV-1 positive mothers have had inconsistent findings and have not explored interactions among risk factors. This study addresses these...

Use of anti-retroviral therapy in tuberculosis patients on second-line anti-TB regimens: A systematic review

2012

INTRODUCTION: Use of antiretroviral therapy (ART) during treatment of drug susceptible tuberculosis (TB) improves survival. However, data from HIV infected individuals with drug resistant TB are lacking. Second line TB...

Mobile phone text messaging for promoting adherence to antiretroviral therapy in patients with HIV infection

2012

BACKGROUND: More than 34 million people are presently living with HIV infection. Antiretroviral therapy (ART) can help these people to live longer, healthier lives, but adherence to ART can be...

The rate of HIV testing is increasing among men who have sex with men in China

2012

OBJECTIVES: HIV infection is spreading relatively quickly among men who have sex with men (MSM) in China. Accurate knowledge of HIV status is of high importance for public health prevention....

Hepatitis C virus infection and risk of coronary artery disease: A systematic review of the literature

2012

Background: Several chronic infections have been associated with cardiovascular diseases, including Chlamydia pneumoniae, human immunodeficiency virus and viral hepatitis. This review evaluates the literature on the association between chronic hepatitis...

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