SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Micronutrient supplementation in children and adults with HIV infection

2010

BACKGROUND: Micronutrient deficiencies are widespread and compound the effects of HIV disease; micronutrient supplements may be effective and safe in reducing this burden. OBJECTIVES: To assess whether micronutrient supplements are...

The efficacy and safety of insulin-sensitizing drugs in HIV-associated lipodystrophy syndrome: A meta-analysis of randomized trials

2010

BACKGROUND:HIV-associated lipodystrophy syndrome (HALS) is characterized by insulin resistance, abnormal lipid metabolism and redistribution of body fat. To date, there has been no quantitative summary of the effects of insulin...

Equity and efficiency in scaling up access to HIV-related interventions in resource-limited settings

2010

Purpose of review: The present review focuses on empirical studies examining equity and efficiency in scaling up access to HIV treatment in resource-limited settings. Key themes from reviewed papers are...

Pharmacological treatment of painful HIV-associated sensory neuropathy: A systematic review and meta-analysis of randomised controlled trials

2010

BACKGROUND: Significant pain from HIV-associated sensory neuropathy (HIV-SN) affects ~40% of HIV infected individuals treated with antiretroviral therapy (ART). The prevalence of HIV-SN has increased despite the more widespread use...

Intravaginal practices, vaginal infections and HIV acquisition: Systematic review and meta-analysis

2010

BACKGROUND: Intravaginal practices are commonly used by women to manage their vaginal health and sexual life. These practices could, however, affect intravaginal mucosal integrity. The objectives of this study were...

Home-based HIV voluntary counselling and testing (VCT) for improving uptake of HIV testing

2010

BACKGROUND: The low uptake of HIV voluntary counselling and testing (VCT) has hindered global attempts to prevent new HIV infections and has limited scale-up of HIV care and treatment. Globally,...

Causal considerations on alcohol and HIV/AIDS: A systematic review

2010

AIM: The study aimed to explore the possible causal nature of the association between alcohol consumption and HIV/AIDS. METHODS: A review based on meta-analyses and reviews was conducted according to...

The effectiveness of highly active antiretroviral therapy among HIV-infected children in Asian countries

2010

Worldwide, there are 2.1 million children under 15 years of age living with HIV infection. In the past five years, there has been significant progress in providing antiretroviral therapy (ART)...

Are we going to close social gaps in HIV? Likely effects of behavioral HIV-prevention interventions on health disparities

2010

Although experimental behavioral interventions to prevent HIV are generally designed to correct undesirable epidemiological trends, it is presently unknown whether the resulting body of behavioral interventions is adequate to correct...

The impact of Prevention of Mother to Child Transmission (PMTCT) programmes on maternal health care in resource-poor settings: Looking beyond the PMTCT programme – a systematic review

2010

BACKGROUND: There is increasing debate about the impact of scaled-up HIV/AIDS programmes on fragile healthcare systems in low-income countries. OBJECTIVES: To contribute to the understanding of the relation between HIV/AIDS...

Sociocultural and epidemiological aspects of HIV/AIDS in Mozambique

2010

Background. A legacy of colonial rule coupled with a devastating 16-year civil war through 1992 left Mozambique economically impoverished just as the human immunodeficiency virus (HIV) epidemic swept over southern...

Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review

2010

Background: Since the mid-1990s, there have been growing efforts to prevent cervical cancer in less-developed countries through the development of innovative screening approaches such as visual inspection of the cervix...

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