SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Estimating the risks of acquiring a kidney abroad: A meta-analysis of complications following participation in transplant tourism

2012

A meta-analysis of odds ratios comparing the risks of participating in transplant tourism by acquiring a kidney abroad to the risks associated with domestic kidney transplant was undertaken. Comparison across...

Decline in HIV prevalence among young women in Zambia: National-level estimates of trends mask geographical and socio-demographic differences

2012

A decline in HIV incidence has been reported in Zambia and a number of other sub-Saharan countries. The trend of HIV prevalence among young people is a good marker of...

Vaginal practices as women’s agency in Sub-Saharan Africa: A synthesis of meaning and motivation through meta-ethnography

2012

This paper reports on a systematic review of qualitative research about vaginal practices in Sub-Saharan Africa, which used meta-ethnographic methods to understand their origins, their meanings for the women who...

Effectiveness and key features of employment support program

2012

Key take-home messages In the literature, employment support programs are typically referred to as “vocational rehabilitation programs” and include two primary approaches: supported employment programs and prevocational training programs. Prevocational...

Effects of interferon-alpha treatment on the incidence of hyperglycemia in chronic hepatitis c patients: A systematic review and meta-analysis

2012

Background: There is a significant association between effects of interferon-alpha treatment and the risk of developing hyperglycemia in patients with chronic hepatitis C virus (HCV) infection. The objective of this...

Relative risk of cardiovascular disease among people living with HIV: A systematic review and meta-analysis

2012

OBJECTIVES: The aim of this study was to estimate the relative risk of cardiovascular disease (CVD) among people living with HIV (PLHIV) compared with the HIV-uninfected population. METHODS: We conducted...

Diarrhea associated with lopinavir/ritonavir-based therapy: Results of a meta-analysis of 1469 HIV-1-infected participants

2012

BACKGROUND: Antiretroviral therapy is associated with adverse events (AEs). The most frequently reported AE associated with lopinavir/ritonavir (LPV/r) containing regimens is diarrhea. The objective of this meta-analysis is to describe...

Effect of CCR5-32 heterozygosity on HIV-1 susceptibility: A meta-analysis

2012

So far, many studies have investigated the distribution of CCR5 genotype between HIV-1 infected patients and uninfected people. However, no definite results have been put forward about whether heterozygosity for...

Predictive value of interferon- release assays for incident active tuberculosis: A systematic review and meta-analysis

2012

Background: We aimed to assess whether interferon- release assays (IGRAs) can predict the development of active tuberculosis and whether the predictive ability of these tests is better than that of...

A review of the virological efficacy of the 4 world health organization-recommended tenofovir-containing regimens for initial HIV therapy

2012

We systematically reviewed studies of the virological efficacy of the 4 new tenofovir (TDF)-containing regimens recommended for initial antiretroviral (ARV) therapy in the 2010 World Health Organization ARV Treatment Guidelines....

Voluntary counseling and testing (VCT) for changing HIV-related risk behavior in developing countries

2012

BACKGROUND: Voluntary counseling and testing (VCT) continues to play a critical role in HIV prevention, care and treatment. In recent years, different modalities of VCT have been implemented, including clinic-,...

Scope and effectiveness of mobile phone messaging for HIV/AIDS care: A systematic review

2012

The objective of this mixed method systematic review was to assess the scope, effectiveness, acceptability and feasibility of the use of mobile phone messaging for HIV infection prevention, treatment and...

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