SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Antihypertensive drugs in patients treated with antiretrovirals

2012

OBJECTIVE: To review the literature for information regarding pharmacokinetic interactions between antiretrovirals and antihypertensive agents, evaluate the clinical significance of these interactions, and analyze the effect of antihypertensive drugs on...

Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: A global collaborative study and meta-regression analysis

2012

BACKGROUND: The emergence and spread of high levels of HIV-1 drug resistance in resource-limited settings where combination antiretroviral treatment has been scaled up could compromise the effectiveness of national HIV...

HIV and HCV prevalence among entrants to methadone maintenance treatment clinics in China: A systematic review and meta-analysis

2012

Background: Methadone maintenance treatment (MMT) was implemented in China since 2004. It was initiated in 8 pilot clinics and subsequently expanded to 738 clinics by the end of 2011. Numerous...

Demographic characteristics associated with access to HAART, HIV care and HIV viral load testing

2012

Key take-home messages In many Canadian studies, issues related to access to HAART are not addressed because it is assumed that everyone in the universal health care system has the...

Tesamorelin: A growth hormone-releasing factor analogue for HIV-associated lipodystrophy

2012

OBJECTIVE: To evaluate the efficacy and safety of tesamorelin, a growth hormone releasing factor analogue approved by the Food and Drug Administration in November 2010 for the treatment of lipodystrophy...

Mental health outcomes in HIV and childhood maltreatment: A systematic review

2012

BACKGROUND: High rates of childhood maltreatment have been documented in HIV-positive men and women. In addition, mental disorders are highly prevalent in both HIV-infected individuals and victims of childhood maltreatment....

Potential benefits of carnitine in HIV-positive patients

2012

Carnitine is a nonessential amino acid that has a central role in lipid peroxidation and mitochondrial metabolism. Carnitine deficiency is rare in adult human subjects who have a normal diet...

Epidemiology of HIV-related neuropathy: A systematic literature review

2012

We sought to identify and summarize the incidence and prevalence of neuropathy among HIV patients and subgroups. A systematic search of the literature was performed using MEDLINE and EMBASE. The...

Impact of hepatitis C co-infection on response to antiretroviral treatment

2012

The MONET study, comparing darunavir/ritonavir-based triple therapy and monotherapy, has found higher risk of failure in patients with positive HCV serology, but the effects of HCV co-infection on the efficacy...

Partner notification uptake for sexually transmitted infections in China: A systematic literature review

2012

Objective: China’s sexually transmitted infection (STI) epidemic requires comprehensive control programmes. Partner services are traditional pillars of STI control but have not been widely implemented in China. This study was...

HIV prevalence amongst injecting drug users in Iran: A systematic review of studies conducted during the decade 1998-2007

2012

Background and objectives: Iran is a country with low HIV prevalence in the general population and concentrated prevalence amongst injecting drug users (IDUs). Various studies have been carried out on...

Use of the Internet for the surveillance and prevention of sexually transmitted diseases

2012

The Internet is a relatively new tool in the surveillance and prevention of sexually transmitted infections, and this review examines its global use in this regard. Much use has been...

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