SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Barriers and facilitators to uptake and use of oral pre-exposure prophylaxis in pregnant and postpartum women: A qualitative meta-synthesis

2024

BACKGROUND: Acute HIV infection during pregnancy and in the postpartum period increases the risk of vertical transmission. The World Health Organization (WHO) has recommended preexposure prophylaxis for pregnant and postpartum...

HBV, HCV and HIV among inmates in Latin America and the Caribbean: A systematic review and meta-analysis

2024

OBJECTIVES: Hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) affect 340 million people worldwide and have a high impact on vulnerable populations. The aim of...

Prevalence of common mental disorder and its association with perceived stigma and social support among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis

2024

Background When common mental disorders (CMD) co-occur with HIV/AIDS, they can complicate patient diagnosis, help-seeking behaviors, quality of life, treatment outcomes, and drug adherence. Thus, estimating the pooled prevalence of...

Patient and public involvement in HIV research: A mapping review and development of an online evidence map

2024

INTRODUCTION: Increasing evidence indicates the benefits of patient and public involvement (PPI) in medical research, and PPI is increasingly expected by funders and publishers. We conducted a mapping review of...

HIV prevention interventions for women who use substances

2024

 Key take-home messages

Exploring intervention frameworks to improve utilization of elimination of mother-to-child transmission services in Africa: A scoping review

2024

BACKGROUND: Over the past two decades, intervention strategies to improve the use of the elimination of mother-to-child transmission (EMTCT) services have been implemented for several reasons. The reasons include elimination...

Dyslipidemia among HIV-infected patients in Ethiopia: A systematic review and meta-analysis

2024

Background Dyslipidemia is responsible for more than half of the global ischemic heart disease (IHD) and more than 4 million deaths annually. Assessing the prevalence of dyslipidemia can be crucial...

Detection rates of mental health problems among sexual minorities in mainland China: A meta-analysis

2024

Previous studies that have addressed the growing mental health problems among sexual minorities in mainland China, but failed to inform mental health programs and public health policies with consistent detection...

Economic evaluations of establishing opioid overdose prevention centers in 12 North American cities: A systematic review

2024

OBJECTIVES: Overdose prevention centers (OPCs) provide a safe place where people can consume preobtained drugs under supervision so that a life-saving medical response can be provided quickly in the event...

Prevalence, clinical features, and predictors of adrenal insufficiency in adults with tuberculosis or HIV: A systematic review and meta-analysis

2024

BACKGROUND: Despite the high frequency of adrenal insufficiency (AI) in patients with tuberculosis or HIV, its diagnosis is often missed or delayed resulting in increased mortality. This systematic review and...

Molecular role of HIV-1 human receptors (CCL5-CCR5 Axis) in neuroAIDS: A systematic review

2024

Chronic HIV-1 infection can cause neurological illness, also known as HIV-associated neurocognitive disorders (HAND). The elevated level of pro-inflammatory cytokines and chemokines, such as C-C Chemokine Ligand 5 (CCL5/RANTES), is...

Adherence and HIV protection thresholds for emtricitabine and tenofovir disoproxil fumarate preexposure prophylaxis among cisgender women: A systematic review

2024

Purpose of review: Adherence-concentration-efficacy benchmarks have not been fully characterized for cisgender women using emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) oral daily pre-exposure prophylaxis (PrEP) for HIV prevention. Recent findings: We conducted a systematic...

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