SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Wealth, income and HIV in sub-Saharan Africa: A systematic review

2025

INTRODUCTION: While economic vulnerability is an established driver of health disparities, the relationships between HIV and wealth, income, and economic inequality have been less consistently established. We conducted a systematic...

Lessons from the field: A systematic review of global and continental prevalence and challenges of people living with HIV (COVID-19)

2025

COVID-19, caused by SARS-CoV-2, accounts for 186 million infections and more than 4 million deaths globally. This systematic review concentrates on the epidemiological profiling of HIV/AIDS, along with the unique...

Prevalence of suicidal ideation and associated factors among perinatal women living with HIV: A systematic review and meta-analysis

2025

Perinatal women living with HIV face increased susceptibility to mental health challenges, including suicidal ideation (SI). This study aimed to determine the prevalence of SI among perinatal women with HIV...

Adherence to antiretroviral therapy and its associated factors among children living with HIV in Eastern and Southern Africa: A systematic review and meta-analysis

2025

Background: Children living with HIV in low-income settings, such as in Eastern and Southern Africa, are at a high risk for poor adherence to antiretroviral therapy. However, various primary studies presented...

Burden of depression among HIV caregivers in India: A systematic review and meta-analysis

2025

Caregivers of individuals living with HIV face significant mental health challenges, with depression being the most common. Despite global research highlighting this burden, studies specific to the Indian context are...

What are the risk factors of non-fatal overdose among persons who use opioids? A systematic review and meta-analysis

2025

Introduction: Non-fatal opioid overdose (NFOD) is a concerning public health issue that is a risk factor for subsequent fatal overdose. Methods: This systematic review aimed to evaluate all the previous literature using...

Climate change and HIV prevention: Towards sustainable solutions—A narrative review

2025

Climate change, with its pervasive environmental, social, and economic impacts, is emerging as a significant factor influencing global health outcomes, including the prevention and management of HIV. The intersection of...

A systematic literature review on pre-exposure prophylaxis as a strategy for HIV risk reduction in the Middle East

2025

Pre-exposure prophylaxis (PrEP) has emerged as a crucial tool in HIV prevention globally, yet its implementation in the Middle East and North Africa (MENA) region faces unique challenges. PrEP is...

Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: A systematic review and meta-analysis

2025

Background Although a growing body of evidence supports zero risk of sexual HIV transmission from a person with sustained virological suppression, known as U=U (undetectable equals untransmittable), data have been...

A meta-analysis of prevalence and moderating factors of malnutrition among people living with HIV across countries

2025

Malnutrition is a critical issue for people living with HIV (PLWH), affecting their immune function, health outcomes, and response to antiretroviral therapy. This meta-analysis assessed the prevalence of malnutrition among...

Better together?: A systematic review of he effectiveness of HIV prevention interventions that build or strengthen social ties

2025

Although social relationships impact health and social dynamics play a key role in shaping HIV vulnerability, results from intentional efforts to build or strengthen social relationships have not been synthesized...

Single-session interventions to enhance HIV outcomes among adolescents and young adults: A systematic scoping review and implications for integrating HIV and mental health services

2025

Significant progress has been made in HIV prevention and treatment for adolescents and young adults (AYA), but integrating mental healthcare remains essential to address risks and improve treatment engagement. Single-session...

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