SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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H1N1 vaccine guidelines for people living with HIV/AIDS (Updated 2010)

2010

Key take-home messages Although there is no specific data on the safety and effectiveness of the H1N1 vaccine — or seasonal flu vaccines — among people with HIV/AIDS, there is...

Treatment of active tuberculosis in HIV-coinfected patients: A systematic review and meta-analysis.

2010

Rationale: Patients with HIV-related tuberculosis (TB) have an increased risk of death, TB treatment failure, and relapse. There are several areas of uncertainty regarding the treatment of active TB in...

Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children

2010

BACKGROUND: Oral candidiasis (OC) associated with human immunodeficiency virus (HIV) infection occurs commonly and recurs frequently, often presenting as an initial manifestation of the disease. Left untreated, these lesions contribute...

Treatment for leiomyosarcoma and leiomyoma in children with HIV infection

2010

BACKGROUND: Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV...

Couples-focused behavioral interventions for prevention of HIV: Systematic review of the state of evidence

2010

HIV is frequently transmitted in the context of partners in a committed relationship, thus couples-focused HIV prevention interventions are a potentially promising modality for reducing infection. We conducted a systematic...

Can computer-mediated interventions change theoretical mediators of safer sex? A meta-analysis

2010

The purpose of this study was to conduct a meta-analysis of computer-mediated interventions (CMIs) aimed at changing theoretical mediators of safer sex. Meta-analytic aggregation of effect sizes from k =...

Transgender men’s sexual health and HIV risk

2010

Key take-home messages There is very little research about transmen’s sexual health, or their rates of HIV and STI infection. Existing research involving relatively small groups of transmen has found...

Weighing the gold in the gold standard: Challenges in HIV prevention research

2010

OBJECTIVE(S): Few HIV prevention interventions have been evaluated in randomized controlled trials (RCTs). We examined design, implementation, and contextual considerations that may limit detection of a positive or adverse effect...

Behavior change interventions to prevent HIV infection among women living in low and middle income countries: A systematic review

2010

We conducted a systematic review of behavioral change interventions to prevent the sexual transmission of HIV among women and girls living in low- and middle-income countries. PubMed/MEDLINE, Web of Science,...

Optimal monitoring strategies for guiding when to switch first-line antiretroviral therapy regimens for treatment failure in adults and adolescents living with HIV in low-resource settings

2010

BACKGROUND: One of the critical clinical decisions made in antiretroviral therapy (ART) is when to switch from an initial regimen to another due to treatment failure. This complex process requires...

Systematic review of interventions to prevent the spread of sexually transmitted infections, including HIV, among young people in Europe

2010

AIM: To examine the effectiveness of interventions seeking to prevent the spread of sexually transmitted infections (STIs), including HIV, among young people in the European Union. METHODS: For this systematic...

Effectiveness of HIV prevention for youth in sub-Saharan Africa: Systematic review and meta-analysis of randomized and nonrandomized trials

2010

Objective: Systematically assess the effectiveness of HIV-prevention interventions in changing sexual behaviour of young people (10-25 years) in sub-Saharan Africa. Methods: Three online databases were searched using prespecified terms. Additional...

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