SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Assessing tuberculosis case fatality ratio: A meta-analysis

2011

BACKGROUND: Recently, the tuberculosis (TB) Task Force Impact Measurement acknowledged the need to review the assumptions underlying the TB mortality estimates published annually by the World Health Organization (WHO). TB...

Facilitating HIV disclosure across diverse settings: A review

2011

HIV status disclosure is central to debates about HIV because of its potential for HIV prevention and its links to privacy and confidentiality as human-rights issues. Our review of the...

Sperm washing to prevent HIV transmission from HIV-infected men but allowing conception in sero-discordant couples

2011

BACKGROUND: Sperm washing is a term used to describe the process in which individual spermatozoa are separated from the seminal fluid. Sperm washing is used to prevent HIV transmission but...

Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: A systematic review

2011

Tuberculosis (TB) is increasing in incidence in certain parts of the world, particularly where there is a co-epidemic of human immunodeficiency virus/acquired immune-deficiency syndrome (HIV/AIDS), and it is associated with...

Peginterferon alfa-2a is superior to peginterferon alfa-2b in the treatment of naïve patients with hepatitis C virus infection: Meta-analysis of randomized controlled trials.

2011

BACKGROUND: Pegylated interferon (PEGIFN) and ribavirin combination is the standard of care for the treatment of chronic hepatitis C virus (HCV) infection. Studies comparing the efficacy and safety of PEGIFN...

Efficacy and safety of zinc supplementation for adults, children and pregnant women with HIV infection: Systematic review

2011

Objectives To determine the efficacy and safety of zinc supplementary in children, adults and pregnant women with HIV infection. Methods We conducted a comprehensive search in Medline, Embase, the Cochrane...

Immunomodulatory effects of intravenous immunoglobulins (IVIGs) in HIV-1 disease: A systematic review

2011

Intravenous immunoglobulins (IVIGs) are generally used as replacement therapy for humoral immunodeficiencies. In consideration of their immune-modulating properties, they are also employed as “immune-modulating/ anti-inflammatory” treatment in different clinical conditions....

Prevalence of hepatitis B and C in HIV-infected patients: A meta-analysis

2011

BACKGROUND: Hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodefciency virus (HIV) share similar routes of transmission by sexual intercourse or drug use by parenteral injection, so coinfection...

Seasonal influenza epidemiology in sub-Saharan Africa: A systematic review

2011

Acute respiratory infection (ARI) is a leading cause of mortality worldwide, of which influenza is an important cause that can be prevented with vaccination. We did a systematic review of...

The role of coinfections in HIV epidemic trajectory and positive prevention: A systematic review and meta-analysis

2011

OBJECTIVES: Recurrent or persistent coinfections may increase HIV viral load and, consequently, risk of HIV transmission, thus increasing HIV incidence. We evaluated the association between malaria, herpes simplex virus type...

Criminalization of HIV exposure or transmission: Stakeholder views and beliefs and effects on behaviour

2011

Key take-home messages There is limited research evidence available to inform each of the questions posed by this review and the findings presented should be interpreted with caution. The available...

Moderators of the relationship between internalized homophobia and risky sexual behavior in men who have sex with men: A meta-analysis

2011

Research on internalized homophobia (IH) has consistently linked it to both mental and physical health outcomes, while research on its relationships with other variables has been inconsistent. Some research and...

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