SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Predictors and treatment strategies of HIV-related fatigue in the combined antiretroviral therapy era

2010

Objective: To assess predictors and reported treatment strategies of HIV-related fatigue in the combined antiretroviral (cART) era. Method: Five databases were searched and reference lists of pertinent articles were checked....

A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy

2010

Objective: To determine the impact of thiazolidinediones (TZD) on changes in limb fat mass in HIV-infected individuals, particularly in those not receiving a thymidine analogue.Methods: Individual patient data from placebo-controlled,...

Knowledge and training needs of health professionals working with people with HIV: With consideration for mixed urban rural care settings

2010

Key take-home messages Despite the availability of improved knowledge and training of healthcare providers, some continue to have negative attitudes and beliefs towards PHAs, which could adversely impact PHA health...

HIV: primary and secondary prophylaxis for opportunistic infections

2010

INTRODUCTION: Opportunistic infections can occur in up to 40% of people with HIV infection and a CD4 count less than 250/mm(3), although the risks are much lower with use of...

Implementation of antiretroviral therapy adherence interventions: A realist synthesis of evidence

2010

AIM: This paper is a report of a synthesis of evidence on implementation of interventions to improve adherence to antiretroviral therapy. BACKGROUND: Evidence on efficacy must be supplemented with evidence...

HIV status in discordant couples in sub-Saharan Africa: A systematic review and meta-analysis

2010

BACKGROUND: Most couples affected by HIV/AIDS in sub-Saharan Africa live in discordant relationships. Men are thought to be the index case in most relationships, and most social marketing and awareness...

Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection

2010

BACKGROUND: Diarrhoea is a major cause of morbidity and mortality among infants and children worldwide, especially in low- and middle-income countries. Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is a condition...

Health and medical research in Nepal: A bibliometric review

2010

This study aimed to quantify the following: (1) health research in academic journals covering Nepal, (2) location of authors, and (3) most prevalent specialties. Published health research conducted in Nepal...

Effect of treating co-infections on HIV-1 viral load: A systematic review

2010

Co-infections contribute to HIV-related pathogenesis and often increase viral load in HIV-infected people. We did a systematic review to assess the effect of treating key co-infections on plasma HIV-1-RNA concentrations...

Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy

2010

BACKGROUND: Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI)...

Nucleoside reverse transcriptase inhibitors in combination therapy for HIV patients: Systematic review and meta-analysis

2010

Treatment guidelines recommend dual nucleoside reverse transcriptase inhibitors (NRTI ) as a part of combination antiretroviral therapy. The objective of this study was to assess the relative efficacy and toxicity...

Antiretroviral therapy (ART) for treating HIV infection in ART-eligible pregnant women

2010

BACKGROUND: This systematic review focuses on antiretroviral therapy (ART) for treating human immunodeficiency virus (HIV) infection in ART-eligible pregnant women. Mother-to-child transmission (MTCT) is the primary means by which children...

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