SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Diverticulitis in transplant patients and patients on chronic corticosteroid therapy: A systematic review

2010

BACKGROUND: The clinical course of diverticular disease in immunosuppressed patients is widely believed to be more severe than in the general population. In this study we systematically reviewed the literature...

High prevalence of drug-resistant tuberculosis and other mycobacteria among HIV-infected patients in Brazil: A systematic review

2010

There is a little-noticed trend involving human immunodeficiency virus (HIV)-infected patients suspected of having tuberculosis: the triple-treatment regimen recommended in Brazil for years has been potentially ineffective in over 30%...

Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis

2010

The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...

Predictors and treatment strategies of HIV-related fatigue in the combined antiretroviral therapy era

2010

Objective: To assess predictors and reported treatment strategies of HIV-related fatigue in the combined antiretroviral (cART) era. Method: Five databases were searched and reference lists of pertinent articles were checked....

HIV prevention for men who have sex with men

2010

Key take-home messages There are very few studies of prevention interventions for MSM that use reliable evaluation outcome measures Self-reports have shown that individual-, group- and community-level interventions are effective...

A critical literature review to identify possible causes of higher rates of HIV infection among young black and Latino men who have sex with men

2010

Black and Latino young men who have sex with men (YMSM) are disproportionately impacted by HIV infection; however, the reason for this disparity is unclear. To identify possible causes of...

Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus

2010

BACKGROUND: Antiviral treatment for chronic hepatitis C may be less effective if patients are co-infected with human immunodeficiency virus (HIV). OBJECTIVES: To assess the benefits and harms of antiviral treatment...

Syphilitic uveitis: A review of clinical manifestations and treatment outcomes of syphilitic uveitis in human immunodeficiency virus-positive and negative patients

2010

The incidence of syphilis and syphilitic uveitis in our community is increasing. The prevalence of associated neurosyphilis is unknown, and it remains unclear whether syphilitic uveitis should be treated as...

A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy

2010

Objective: To determine the impact of thiazolidinediones (TZD) on changes in limb fat mass in HIV-infected individuals, particularly in those not receiving a thymidine analogue.Methods: Individual patient data from placebo-controlled,...

Knowledge and training needs of health professionals working with people with HIV: With consideration for mixed urban rural care settings

2010

Key take-home messages Despite the availability of improved knowledge and training of healthcare providers, some continue to have negative attitudes and beliefs towards PHAs, which could adversely impact PHA health...

HIV: primary and secondary prophylaxis for opportunistic infections

2010

INTRODUCTION: Opportunistic infections can occur in up to 40% of people with HIV infection and a CD4 count less than 250/mm(3), although the risks are much lower with use of...

Implementation of antiretroviral therapy adherence interventions: A realist synthesis of evidence

2010

AIM: This paper is a report of a synthesis of evidence on implementation of interventions to improve adherence to antiretroviral therapy. BACKGROUND: Evidence on efficacy must be supplemented with evidence...

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