SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effect of medication dosing frequency on adherence in chronic diseases

2009

OBJECTIVE: To systematically review available data on the effect of daily medication dosing frequency on medication adherence in chronic disease states, as assessed by precise medication event monitoring systems (MEMS)....

Etravirine: a second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant strains of HIV

2009

BACKGROUND: Since 1981, the AIDs epidemic has continued to expand and, at the end of 2007, there were ~33 million people worldwide living with HIV, including 1.2 million in North...

Massage and recreation therapy for reducing stress for people living with HIV

2009

Key take-home messages There are few studies on the effects of massage on stress, quality of life or immune measures for people living with HIV/AIDS as two systematic reviews (one...

Meta-analysis of health and demographic correlates of stigma towards people living with HIV

2009

HIV-related stigma may negatively impact the health, quality of life, social support and well-being of people living with HIV (PLHIV). Previous studies have used diverse samples and a multitude of...

Impact of hepatitis B virus infection on the progression of AIDS and mortality in HIV-infected individuals: A cohort study and meta-analysis

2009

Background. The effect of hepatitis B virus (HBV) infection on the natural history of human immunodeficiency virus (HIV) disease remains uncertain. Therefore, a retrospective cohort study was conducted to examine...

Impact of human immunodeficiency virus infection on the course of hepatitis C virus infection: A meta-analysis

2009

Aim: To analyze the influence of human immunodeficiency virus (HIV) infection on the course of hepatitis C virus (HCV) infection. Methods: We performed a meta-analysis to quantify the effect of...

A systematic review of the quality of trials evaluating biomedical HIV prevention interventions shows that many lack power

2009

Purpose: Several randomized, controlled trials (RCTs) have tested strategies to prevent sexual acquisition of HIV infection, but their quality has been variable. We aimed to identify, describe, and evaluate the...

Hepatotoxicity associated with long- versus short-course HIV-prophylactic nevirapine use: A systematic review and meta-analysis from the Research on Adverse Drug events And Reports (RADAR) project

2009

Background and objective: The antiretroviral nevirapine can cause severe hepatotoxicity when used ‘off-label’ for preventing mother-to-child HIV transmission (PMTCT), newborn post-exposure prophylaxis and for pre- and post-exposure prophylaxis among non-HIV-infected...

Effects of prenatal multimicronutrient supplementation on pregnancy outcomes: A meta-analysis

2009

XST: This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each critical abstract contains a brief summary of the review methods, results...

The effectiveness of behavioural and psychosocial HIV/STI prevention interventions for MSM in Europe: A systematic review

2009

Given the need of programme planners and policy makers for descriptions of specific interventions and quantitative estimates of intervention effects to make informed decisions concerning prevention funding and research, there...

Prevalence of unprotected anal intercourse among HIV-diagnosed MSM in the United States: A meta-analysis

2009

OBJECTIVE: To integrate the empirical findings on the prevalence of unprotected anal intercourse (UAI) among HIV-diagnosed men who have sex with men (MSM) in the United States. METHODS: Comprehensively searching...

Evidence behind the WHO guidelines: Hospital care for children: What is the role of HIV antigen testing in infants < 12-months old?

2009

The World Health Organization has produced guidelines for the management of common illnesses in hospitals with limited resources. This series reviews the scientific evidence behind WHO’s recommendations. The WHO guidelines,...

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