SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Optimal time for initiation of antiretroviral therapy in asymptomatic, HIV-infected, treatment-naive adults

2010

BACKGROUND: According to consensus, initiation of therapy is best based on CD4 cell count, a marker of immune status, rather than on viral load, a marker of virologic replication. For...

HIV and hepatitis B and C incidence rates in US correctional populations and high risk groups: A systematic review and meta-analysis

2010

BACKGROUND: High Human Immunodeficiency Virus (HIV) prevalence and high risk behaviors have been well documented within United States (US) correctional systems. However, uncertainty remains regarding the extent to which placing...

Epidemiology of HIV infection in the Middle East and North Africa

2010

OBJECTIVE: The Middle East and North Africa (MENA) region continues to be perceived as a region with very limited HIV epidemiological data, raising many controversies about the status of the...

Weighing the gold in the gold standard: Challenges in HIV prevention research

2010

OBJECTIVE(S): Few HIV prevention interventions have been evaluated in randomized controlled trials (RCTs). We examined design, implementation, and contextual considerations that may limit detection of a positive or adverse effect...

Academic achievement and psychosocial needs of children affected by or infected with HIV/AIDS

2010

Key take-home messages There is very little research that directly examines the long-term academic achievement or the psychosocial needs of children affected by HIV. Of the studies that do exist...

Psychosocial interventions for the reduction of injection and sexual risk behaviour for preventing HIV in drug users

2010

BACKGROUND: Drug users (including both injection drug users and crack cocaine users), are at high levels of risk for contracting HIV. Therefore it is important to reduce the injection and/or...

Applicability and generalisability of the results of systematic reviews to public health practice and policy: A systematic review

2010

BACKGROUND: The purpose of the study was to evaluate systematic reviews of research into two public health priorities, tobacco consumption and HIV infection, in terms of the reporting of data...

Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children

2010

BACKGROUND: Oral candidiasis (OC) associated with human immunodeficiency virus (HIV) infection occurs commonly and recurs frequently, often presenting as an initial manifestation of the disease. Left untreated, these lesions contribute...

Barriers to HIV testing in Europe: A systematic review

2010

In the European Union (EU) and neighbouring countries, HIV/AIDS, of all infectious diseases, has one of the highest morbidity and mortality rates. An estimated 30% of people living with HIV...

Treatment of active tuberculosis in HIV-coinfected patients: A systematic review and meta-analysis

2010

BACKGROUND: Patients with human immunodeficiency virus (HIV) infection and tuberculosis have an increased risk of death, treatment failure, and relapse. METHODS: A systematic review and meta-analysis of randomized, controlled trials...

Behavioural interventions for HIV positive prevention in developing countries: A systematic review and meta-analysis

2010

Objective To assess the evidence for a differential effect of positive prevention interventions among individuals infected and not infected with human immunodeficiency virus (HIV) in developing countries, and to assess...

People who use drugs, HIV, and human rights

2010

We reviewed evidence from more than 900 studies and reports on the link between human rights abuses experienced by people who use drugs and vulnerability to HIV infection and access...

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