SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Prevalence of oral human papillomavirus infection in African countries: A systematic review and meta-analysis

2025

This meta-analysis aimed to provide pooled overall prevalence estimates of oral human papillomavirus (HPV) infection in Africa. A literature search for cross-sectional studies was conducted until January 2025. The Newcastle-Ottawa...

Morbidity and mortality risk among people with HIV and central or visceral adiposity: A targeted literature review

2025

BACKGROUND: Given the known relationship between human immunodeficiency virus (HIV), antiretroviral therapies, and excess visceral adipose tissue (VAT), this review sought to characterize risk of negative health outcomes associated with...

Use of self-test to increase HIV testing among men who have sex with men and transgender women—Overview of systematic reviews

2025

ABSTRACT Human Immunodeficiency Virus (HIV) infection is stigmatizing, especially for key populations, who are disproportionately affected by Sexually Transmitted Infections (STIs). The stigma and discrimination suffered by these groups are...

Immunogenicity and safety of the booster COVID-19 vaccine among people with HIV: A systematic review and meta-analysis

2025

Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...

Lenacapavir: A twice-yearly injectable for HIV preexposure prophylaxis

2025

OBJECTIVE: To review the efficacy and safety of lenacapavir for the prevention of HIV-1 infection. DATA SOURCES: Clinical trials and review articles were obtained through August 2025 using search terms...

Deep sequencing reveals underestimated burden of integrase inhibitor resistance mutations in people living with HIV: A global individual patient data meta-analysis

2025

Integrase strand transfer inhibitors (INSTIs) have emerged as cornerstone agents in global antiretroviral therapy, though growing drug resistance presents clinical challenges. Conventional Sanger sequencing may underestimate the burden of low-frequency...

Screening and prevention of HPV-related anogenital cancers in women living with HIV in Europe: Results from a systematic review

2024

Background Women living with HIV (WLWH) are at increased risk of human papillomavirus (HPV)-related cancers. Throughout Europe, there is great heterogeneity among guidelines for screening programmes, access to HPV testing...

Increased stigma, and physical and sexual violence against men who have sex with men and transgender women in sub-Saharan Africa: A qualitative evidence synthesis analyzing social and structural barriers to HIV testing and coping behaviors

2024

In sub-Saharan Africa, accessing HIV testing services is a significant challenge for men who have sex with men (MSM) and transgender women (TGW). In this qualitative evidence synthesis, our aim...

Understanding effective post-test linkage strategies for HIV prevention and care: A scoping review

2024

Introduction Following HIV testing services (HTS), the World Health Organization recommends prompt linkage to prevention and treatment. Scale‐up of effective linkage strategies is essential to achieving the global 95‐95‐95 goals...

Exploring optimal HAART adherence rates in Ethiopian adults: A systematic review and meta-analysis

2024

BACKGROUND: Optimal medication adherence is vital for the successful implementation of highly active antiretroviral therapy (HAART) in managing HIV infection. Global efforts aim to minimize the burden of antimicrobial resistance...

Mapping evidence on barriers to and facilitators of diagnosing noncommunicable diseases among people living with human immunodeficiency virus in low- and middle-income countries in Africa: A scoping review

2024

OBJECTIVES: To map the evidence on the barriers to and facilitators of diagnosing noncommunicable diseases among people living with HIV in low- and middle-income countries in Africa. INTRODUCTION: Noncommunicable diseases...

Variation of adverse drug events in different settings in Africa: A systematic review

2024

BACKGROUND: Adverse drug events (ADEs) represent challenges affecting Africa’s healthcare systems owing to the increased healthcare expenditure and negative health outcomes of ADEs. OBJECTIVES: We aimed to systematically review published...

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