SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The efficacy and safety of insulin-sensitizing drugs in HIV-associated lipodystrophy syndrome: A meta-analysis of randomized trials

2010

BACKGROUND:HIV-associated lipodystrophy syndrome (HALS) is characterized by insulin resistance, abnormal lipid metabolism and redistribution of body fat. To date, there has been no quantitative summary of the effects of insulin...

Equity and efficiency in scaling up access to HIV-related interventions in resource-limited settings

2010

Purpose of review: The present review focuses on empirical studies examining equity and efficiency in scaling up access to HIV treatment in resource-limited settings. Key themes from reviewed papers are...

HIV: primary and secondary prophylaxis for opportunistic infections

2010

INTRODUCTION: Opportunistic infections can occur in up to 40% of people with HIV infection and a CD4 count less than 250/mm(3), although the risks are much lower with use of...

HIV prevention for men who have sex with men

2010

Key take-home messages There are very few studies of prevention interventions for MSM that use reliable evaluation outcome measures Self-reports have shown that individual-, group- and community-level interventions are effective...

Hepatitis B/C and HIV in sub-Saharan Africa: an association between highly prevalent infectious diseases. A systematic review and meta-analysis

2010

OBJECTIVES: Hepatitis B virus (HBV), hepatitis C virus (HCV), and the human immunodeficiency virus (HIV) are endemic in Africa. However, hepatitis co-infection rates among HIV-infected individuals remain controversial. The aim...

Causal considerations on alcohol and HIV/AIDS: A systematic review

2010

AIM: The study aimed to explore the possible causal nature of the association between alcohol consumption and HIV/AIDS. METHODS: A review based on meta-analyses and reviews was conducted according to...

The effectiveness of highly active antiretroviral therapy among HIV-infected children in Asian countries

2010

Worldwide, there are 2.1 million children under 15 years of age living with HIV infection. In the past five years, there has been significant progress in providing antiretroviral therapy (ART)...

A review of HIV prevention interventions for juvenile offenders

2010

OBJECTIVE: To conduct a critical review of all HIV prevention intervention studies conducted with adolescents in juvenile justice settings to inform future intervention development. METHOD: PubMed and PsycInfo database searches...

Sociocultural and epidemiological aspects of HIV/AIDS in Mozambique

2010

Background. A legacy of colonial rule coupled with a devastating 16-year civil war through 1992 left Mozambique economically impoverished just as the human immunodeficiency virus (HIV) epidemic swept over southern...

Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review

2010

Background: Since the mid-1990s, there have been growing efforts to prevent cervical cancer in less-developed countries through the development of innovative screening approaches such as visual inspection of the cervix...

Does opioid substitution treatment in prisons reduce injecting-related HIV risk behaviours? A systematic review

2010

OBJECTIVES: To review systematically the evidence on opioid substitution treatment (OST) in prisons in reducing injecting-related human immunodeficiency virus (HIV) risk behaviours. METHODS: Systematic review in accordance with guidelines of...

HIV transmission risk through anal intercourse: Systematic review, meta-analysis and implications for HIV prevention

2010

BACKGROUND: The human immunodeficiency virus (HIV) infectiousness of anal intercourse (AI) has not been systematically reviewed, despite its role driving HIV epidemics among men who have sex with men (MSM)...

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