SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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How long do nosocomial pathogens persist on inanimate surfaces? A systematic review

2006

BACKGROUND: Inanimate surfaces have often been described as the source for outbreaks of nosocomial infections. The aim of this review is to summarize data on the persistence of different nosocomial...

Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: A meta-analytic review

2006

INTRODUCTION: Prevalence estimates of osteopenia and osteoporosis (reduced bone mineral density; BMD) in HIV-infected patients and the role of antiretroviral therapy (ART) varies in the literature. METHODS: We conducted a...

The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health State-of-the-Science Conference

2006

BACKGROUND: Multivitamin and mineral supplements are the most commonly used dietary supplements in the United States. PURPOSE: To synthesize studies on the efficacy and safety of multivitamin/mineral supplement use in...

Stigma associated with AIDS: A meta-analysis

2006

Performed a meta-analysis of 21 studies (1986-1993) to determine the degree of stigma associated with AIDS compared to the degree of stigma associated with other comparable conditions (i.e., hepatitis, herpes,...

A meta-analysis of the effectiveness of alternative HIV counseling and testing methods to increase knowledge of HIV status

2006

BACKGROUND: Alternatives to conventional HIV counseling and testing (HIV-CT) have been used to improve receipt of HIV test results. OBJECTIVES: To determine the effectiveness of alternative HIV-CT methods on the...

A review of anti-D treatment of childhood idiopathic thrombocytopenic purpura

2006

Treatment of childhood idiopathic thrombocytopenic purpura is still an area of controversy. We reviewed the literature on anti-D treatment. Most studies used intravenous anti-D. Single doses of 50 microg/kg increased...

What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review

2006

The expansion of AIDS treatment initiatives in resource-poor settings provides an opportunity for integrating mental health care into these programs. This systematic review of the literature on HIV and mental...

A decade in review: Building on the experiences of past adolescent STI/HIV interventions to optimise future prevention efforts

2006

The major purpose of this article is to systematically review and synthesise empirical findings from selected adolescent STI/HIV interventions conducted in the United States between 1994 and 2004. Specifically, the...

Management of toxoplasmic encephalitis in HIV-infected adults (with an emphasis on resource-poor settings)

2006

BACKGROUND: Cerebral toxoplasmosis or toxoplasmic meningoencephalitis (hereafter referred to as TE) was one of the first opportunistic infections to be described in human immunodeficiency virus (HIV) -infected patients. Treatment of...

Efficacy of inactivated hepatitis a vaccine in HIV-infected patients: A hierarchical Bayesian meta-analysis

2006

Patients with human immunodeficiency virus-1 (HIV) have elevated risk for hepatitis A virus (HAV) coinfection. Sequelae from coinfection include increased risk of liver-related morbidity and mortality. This study synthesizes the...

Herpes simplex virus 2 infection increases HIV acquisition in men and women: Systematic review and meta-analysis of longitudinal studies

2006

OBJECTIVE: To estimate the sex-specific effect of herpes simplex virus type 2 (HSV-2) on the acquisition of HIV infection. BACKGROUND: The increased number of longitudinal studies available since the last...

Sexual risk reduction for persons living with HIV: Research synthesis of randomized controlled trials, 1993 to 2004

2006

OBJECTIVE: To conduct a meta-analytic review of interventions to reduce HIV individuals’ sexual risk. DESIGN: Studies were included if they examined a deliberate sexual risk-reduction strategy in a sample that...

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