SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV-associated anemia in children: A systematic review from a global perspective

2008

Objectives:: To assess the importance of anemia in HIV-infected children in western and tropical settings. Design:: A systematic review with a descriptive component. Methods:: Four databases were searched and reference...

The unique features of pediatric HIV-1 in sub-Saharan Africa

2008

In order to adapt African programs for antiretroviral treatment (ART) to children’s needs, a good understanding of the unique features of pediatric HIV in Africa and realistic expectations of the...

Switching from suppressive protease inhibitor-based regimens to nevirapine-based regimens: A meta-analysis of randomized controlled trials

2008

OBJECTIVES: We performed a meta-analysis to assess the efficacy and safety of switching from protease inhibitor (PI)- to nevirapine (NVP)-based regimens in HIV-infected patients in whom virological suppression had been...

Vertically acquired paediatric HIV infection: the challenges of providing comprehensive packages of care in resource-limited settings

2008

The successes achieved in paediatric disease management in well-resourced countries in recent years highlight the vast divide between the care options, and ultimately survival, between developed and developing areas of...

Impact of small reductions in plasma HIV RNA levels on the risk of heterosexual transmission and disease progression

2008

OBJECTIVE: To estimate the impact of small changes in plasma levels of HIV-1 RNA on the risk of heterosexual transmission or disease progression to an AIDS-defining event or death. DESIGN...

HIV: Treating Pneumocystis pneumonia (PCP)

2008

INTRODUCTION: Pneumocystis pneumonia (PCP) is a common AIDS-defining opportunistic illness in people with HIV infection, but its incidence has fallen with use of prophylactic treatment. Without treatment, PCP is likely...

Maternal infection and risk of preeclampsia: Systematic review and metaanalysis

2008

There are lingering questions regarding the association between maternal infection and preeclampsia. Systematic review and metaanalysis was conducted of observational studies that examined the relationship between maternal infection and preeclampsia....

Peginterferon vs. interferon in the treatment of different HCV genotype infections in HIV patients

2008

It remains difficult to achieve high sustained response rates (SVRs) in chronic hepatitis patients coinfected with human immunodeficiency virus (HIV). The aim of this study was to perform a meta-analysis...

Using respondent-driven sampling methodology for HIV biological and behavioral surveillance in international settings: A systematic review

2008

To determine operational and analytical characteristics of respondent-driven sampling (RDS) in international settings and to explore factors that may affect recruitment of most-at-risk populations using RDS, we reviewed HIV biological...

HIV: Mother to child transmission

2008

Introduction: Over 2 million children are thought to be living with HIV/AIDS worldwide, of whom over 80% live in sub-Saharan Africa. Without anti-retroviral treatment, the risk of HIV transmission from...

The impact of participation in performing arts on adolescent health and behaviour: A systematic review of the literature

2008

This article reports a systematic review of literature published between 1994 and 2004 on the effects of performing arts for health in young people aged 11-18. The review includes research...

Adjunctive therapies for AIDS dementia complex

2008

Background: AIDS dementia complex is a common complication of human immunodeficiency virus type 1 (HIV-1) that continues to exist despite the current use of potent antiretroviral therapy. It is a...

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