SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review

2006

The expansion of AIDS treatment initiatives in resource-poor settings provides an opportunity for integrating mental health care into these programs. This systematic review of the literature on HIV and mental...

A decade in review: Building on the experiences of past adolescent STI/HIV interventions to optimise future prevention efforts

2006

The major purpose of this article is to systematically review and synthesise empirical findings from selected adolescent STI/HIV interventions conducted in the United States between 1994 and 2004. Specifically, the...

Management of toxoplasmic encephalitis in HIV-infected adults (with an emphasis on resource-poor settings)

2006

BACKGROUND: Cerebral toxoplasmosis or toxoplasmic meningoencephalitis (hereafter referred to as TE) was one of the first opportunistic infections to be described in human immunodeficiency virus (HIV) -infected patients. Treatment of...

Efficacy of inactivated hepatitis a vaccine in HIV-infected patients: A hierarchical Bayesian meta-analysis

2006

Patients with human immunodeficiency virus-1 (HIV) have elevated risk for hepatitis A virus (HAV) coinfection. Sequelae from coinfection include increased risk of liver-related morbidity and mortality. This study synthesizes the...

Sexual risk reduction for persons living with HIV: Research synthesis of randomized controlled trials, 1993 to 2004

2006

OBJECTIVE: To conduct a meta-analytic review of interventions to reduce HIV individuals’ sexual risk. DESIGN: Studies were included if they examined a deliberate sexual risk-reduction strategy in a sample that...

Systematic review of the safety of trimethoprim-sulfamethoxazole for prophylaxis in HIV-infected pregnant women: Implications for resource-limited settings

2006

Daily prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMZ) significantly decreases morbidity and mortality among people living with HIV. Some clinicians are reluctant to use TMP-SMZ in pregnant and breastfeeding HIV-infected women because of...

The effectiveness of community interventions targeting HIV and AIDS prevention at young people in developing countries

2006

OBJECTIVE: To identify successful HIV/AIDS prevention interventions targeting youths and delivered in geographically bounded communities (for example, rural villages, urban settlements or neighbourhoods) in developing countries. METHODS: A systematic review...

Risk factors for multidrug resistant tuberculosis in Europe: A systematic review

2006

BACKGROUND: The resurgence of tuberculosis (TB) in western countries has been attributed to the HIV epidemic, immigration, and drug resistance. Multidrug resistant tuberculosis (MDR-TB) is caused by the transmission of...

Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: A systematic review

2006

In low-income and middle-income countries, direct (unconcentrated) sputum smear microscopy is the primary method for diagnosing pulmonary tuberculosis. The method is fast, inexpensive, and specific for Mycobacterium tuberculosis in high...

Net benefits of resistance testing directed therapy compared with standard of care in HIV-infected patients with virological failure: A meta-analysis

2006

BACKGROUND: We incorporated the latest available information to evaluate the net benefit of using resistance testing in HIV-infected patients with virological failure. METHODS: Meta-analysis of randomized controlled trials comparing the...

Rifampicin plus pyrazinamide versus isoniazid for treating latent tuberculosis infection: A meta-analysis

2006

SETTING: Six trials from Haiti, Mexico, the U.S.A., Brazil, Spain, Zambia and Hong Kong. OBJECTIVE: To evaluate the efficacy and safety of rifampicin plus pyrazinamide (RZ) vs. isoniazid (INH) for...

Effects of music and music therapy on medical patients: A meta-analysis of the research and implications for the future

2006

Although the literature examining the effects of music medicine or music therapy interventions in medical settings is both large and growing, this literature is difficult to summarize because of of...

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