SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A meta-analysis of the effectiveness of alternative HIV counseling and testing methods to increase knowledge of HIV status

2006

BACKGROUND: Alternatives to conventional HIV counseling and testing (HIV-CT) have been used to improve receipt of HIV test results. OBJECTIVES: To determine the effectiveness of alternative HIV-CT methods on the...

A review of anti-D treatment of childhood idiopathic thrombocytopenic purpura

2006

Treatment of childhood idiopathic thrombocytopenic purpura is still an area of controversy. We reviewed the literature on anti-D treatment. Most studies used intravenous anti-D. Single doses of 50 microg/kg increased...

What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review

2006

The expansion of AIDS treatment initiatives in resource-poor settings provides an opportunity for integrating mental health care into these programs. This systematic review of the literature on HIV and mental...

A decade in review: Building on the experiences of past adolescent STI/HIV interventions to optimise future prevention efforts

2006

The major purpose of this article is to systematically review and synthesise empirical findings from selected adolescent STI/HIV interventions conducted in the United States between 1994 and 2004. Specifically, the...

Management of toxoplasmic encephalitis in HIV-infected adults (with an emphasis on resource-poor settings)

2006

BACKGROUND: Cerebral toxoplasmosis or toxoplasmic meningoencephalitis (hereafter referred to as TE) was one of the first opportunistic infections to be described in human immunodeficiency virus (HIV) -infected patients. Treatment of...

Efficacy of inactivated hepatitis a vaccine in HIV-infected patients: A hierarchical Bayesian meta-analysis

2006

Patients with human immunodeficiency virus-1 (HIV) have elevated risk for hepatitis A virus (HAV) coinfection. Sequelae from coinfection include increased risk of liver-related morbidity and mortality. This study synthesizes the...

Herpes simplex virus 2 infection increases HIV acquisition in men and women: Systematic review and meta-analysis of longitudinal studies

2006

OBJECTIVE: To estimate the sex-specific effect of herpes simplex virus type 2 (HSV-2) on the acquisition of HIV infection. BACKGROUND: The increased number of longitudinal studies available since the last...

School-based teenage pregnancy prevention programs: A systematic review of randomized controlled trials

2005

We compared school-based abstinence-only programs with those including contraceptive information (abstinence-plus) to determine which has the greatest impact on teen pregnancy. The United States has one of the highest rates...

Intravaginal practices, bacterial vaginosis, and women’s susceptibility to HIV infection: Epidemiological evidence and biological mechanisms

2005

Intravaginal practices such as “dry sex” and douching have been suggested as a risk factor that may increase women’s susceptibility to HIV infection. These behaviours appear common in different populations...

Randomised controlled trials in Africa of HIV and AIDS: Descriptive study and spatial distribution

2005

OBJECTIVES: To identify and describe randomised controlled trials on HIV and AIDS conducted in Africa and to map their spatial distribution using exact geographic coordinates. DESIGN: Construction and analysis of...

Impact of hepatitis C virus on immune restoration in HIV-infected patients who start highly active antiretroviral therapy: A meta-analysis

2005

BACKGROUND: There are conflicting data in the medical literature regarding the degree of immune restoration (as measured by CD4 cell count) in patients who commence highly active antiretroviral therapy (HAART)...

Is chronic HIV infection associated with venous thrombotic disease? A systematic review

2005

Infection with the human immunodeficiency virus (HIV) is still a major health problem world-wide. HIV infection has changed into a chronic infection with the chance of developing long-term complications. Vascular...

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